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5wlp

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Current revision (10:29, 14 June 2023) (edit) (undo)
 
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==Solution structure of the pseudo-receiver domain of Atg32==
==Solution structure of the pseudo-receiver domain of Atg32==
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<StructureSection load='5wlp' size='340' side='right'caption='[[5wlp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='5wlp' size='340' side='right'caption='[[5wlp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wlp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WLP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wlp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WLP FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG32, ECM17, YIL146C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wlp OCA], [https://pdbe.org/5wlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wlp RCSB], [https://www.ebi.ac.uk/pdbsum/5wlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wlp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wlp OCA], [http://pdbe.org/5wlp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wlp RCSB], [http://www.ebi.ac.uk/pdbsum/5wlp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wlp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ATG32_YEAST ATG32_YEAST]] Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation.<ref>PMID:19770589</ref> <ref>PMID:19619494</ref> <ref>PMID:19619495</ref> <ref>PMID:19793921</ref> <ref>PMID:21576396</ref> <ref>PMID:22914317</ref> <ref>PMID:22643220</ref> <ref>PMID:22157017</ref> <ref>PMID:22308029</ref>
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[https://www.uniprot.org/uniprot/ATG32_YEAST ATG32_YEAST] Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation.<ref>PMID:19770589</ref> <ref>PMID:19619494</ref> <ref>PMID:19619495</ref> <ref>PMID:19793921</ref> <ref>PMID:21576396</ref> <ref>PMID:22914317</ref> <ref>PMID:22643220</ref> <ref>PMID:22157017</ref> <ref>PMID:22308029</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pellegrini, M]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Ragusa, M J]]
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[[Category: Pellegrini M]]
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[[Category: Xue, X]]
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[[Category: Ragusa MJ]]
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[[Category: Atg32]]
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[[Category: Xue X]]
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[[Category: Protein transport]]
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[[Category: Pseudo-receiver domain]]
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Current revision

Solution structure of the pseudo-receiver domain of Atg32

PDB ID 5wlp

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