6nva

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Current revision (07:00, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6nva' size='340' side='right'caption='[[6nva]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
<StructureSection load='6nva' size='340' side='right'caption='[[6nva]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6nva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NVA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6nva]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NVA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=RF9:'>RF9</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RF9:N~6~-[(1R)-1-carboxyethyl]-L-lysine'>RF9</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapA, A8C65_04230 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nva OCA], [https://pdbe.org/6nva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nva RCSB], [https://www.ebi.ac.uk/pdbsum/6nva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nva ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_synthase 4-hydroxy-tetrahydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.7 4.3.3.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nva OCA], [http://pdbe.org/6nva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nva RCSB], [http://www.ebi.ac.uk/pdbsum/6nva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nva ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A066Q637_ECOLX A0A066Q637_ECOLX]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418][SAAS:SAAS00570606]
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[https://www.uniprot.org/uniprot/A0A066Q637_ECOLX A0A066Q637_ECOLX] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418][SAAS:SAAS00570606]
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==See Also==
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*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chooback, L]]
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[[Category: Chooback L]]
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[[Category: Thomas, L M]]
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[[Category: Thomas LM]]
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[[Category: Biosynthetic protein]]
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[[Category: Synthase lysine biosynthesis propionate]]
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Current revision

Crystal structure of Escherichia coli dihydrodipicolinate synthase and propionate covalently bound to K161.

PDB ID 6nva

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