Factor VIII

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[2r7e]], [[3cdz]], [[3j2q]], [[4bdv]] – hFVIII – human<br />
+
[[2r7e]], [[3cdz]], [[3j2q]], [[4bdv]], [[6mf2]] – hFVIII – human<br />
[[3hnb]], [[3hny]], [[3hob]] – hFVIII light chain C2 domain<br />
[[3hnb]], [[3hny]], [[3hob]] – hFVIII light chain C2 domain<br />
[[1d7p]] - hFVIII light chain C2 domain (mutant)<br />
[[1d7p]] - hFVIII light chain C2 domain (mutant)<br />
Line 38: Line 38:
[[3j2s]] - hFVIII light chain<br />
[[3j2s]] - hFVIII light chain<br />
[[5k8d]] - hFVIII heavy chain + light chain residus 104-329<br />
[[5k8d]] - hFVIII heavy chain + light chain residus 104-329<br />
-
[[4mo3]] - FVIII light chain C2 domain – pig<br />
+
[[4mo3]] - pFVIII light chain C2 domain – pig<br />
 +
[[6mf0]] – p/hFVIII<br />
== References ==
== References ==
<references/>
<references/>

Revision as of 09:06, 26 July 2020

Glycosylated human Factor VIII. Residues 19-760 (cyan), 1582-2351 (magenta) complex with Ca+2 (green) and Cu+2 (orange) ions (PDB code 2r7e)

Drag the structure with the mouse to rotate

3D Structures of Factor VIII

Updated on 26-July-2020

2r7e, 3cdz, 3j2q, 4bdv, 6mf2 – hFVIII – human
3hnb, 3hny, 3hob – hFVIII light chain C2 domain
1d7p - hFVIII light chain C2 domain (mutant)
1cfg, 1fac - hFVIII light chain C2 domain membrane-binding peptide - NMR
1iqd - hFVIII light chain C2 domain (mutant) + monoclonal Fab
4xzu - hFVIII light chain C2 domain + monoclonal Fab
4pt6 - hFVIII discoidin domain
4ki5 - mFVIII light chain C2 domain + monoclonal Fab – mouse
3j2s - hFVIII light chain
5k8d - hFVIII heavy chain + light chain residus 104-329
4mo3 - pFVIII light chain C2 domain – pig
6mf0 – p/hFVIII

References

  1. ↑ White GC 2nd, Shoemaker CB. Factor VIII gene and hemophilia A. Blood. 1989 Jan;73(1):1-12. PMID:2491949
  2. ↑ Shen BW, Spiegel PC, Chang CH, Huh JW, Lee JS, Kim J, Kim YH, Stoddard BL. The tertiary structure and domain organization of coagulation factor VIII. Blood. 2008 Feb 1;111(3):1240-7. Epub 2007 Oct 26. PMID:17965321 doi:10.1182/blood-2007-08-109918

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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