1aa7

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[[Image:1aa7.gif|left|200px]]
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{{STRUCTURE_1aa7| PDB=1aa7 | SCENE= }}
{{STRUCTURE_1aa7| PDB=1aa7 | SCENE= }}
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'''INFLUENZA VIRUS MATRIX PROTEIN CRYSTAL STRUCTURE AT PH 4.0'''
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===INFLUENZA VIRUS MATRIX PROTEIN CRYSTAL STRUCTURE AT PH 4.0===
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==Overview==
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Matrix protein (M1) of influenza virus is a bifunctional protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. It is therefore required that M1 binds both membrane and RNA simultaneously. The X-ray crystal structure of the N-terminal portion of type A influenza virus M1-amino acid residues 2-158-has been determined at 2.08 A resolution at pH 4.0. The protein forms a dimer. A highly positively charged region on the dimer surface is suitably positioned to bind RNA while the hydrophobic surface opposite the RNA binding region may be involved in interactions with the membrane. The membrane-binding hydrophobic surface could be buried or exposed after a conformational change.
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(as it appears on PubMed at http://www.pubmed.gov), where 9164466 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9164466}}
==About this Structure==
==About this Structure==
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[[Category: Viral assembly]]
[[Category: Viral assembly]]
[[Category: Virion budding]]
[[Category: Virion budding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:02:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:28:44 2008''

Revision as of 13:28, 30 June 2008

Image:1aa7.png

Template:STRUCTURE 1aa7

INFLUENZA VIRUS MATRIX PROTEIN CRYSTAL STRUCTURE AT PH 4.0

Template:ABSTRACT PUBMED 9164466

About this Structure

1AA7 is a Single protein structure of sequence from Unidentified influenza virus. Full crystallographic information is available from OCA.

Reference

Structure of a bifunctional membrane-RNA binding protein, influenza virus matrix protein M1., Sha B, Luo M, Nat Struct Biol. 1997 Mar;4(3):239-44. PMID:9164466

Page seeded by OCA on Mon Jun 30 16:28:44 2008

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