Sandbox Reserved 1095
From Proteopedia
(Difference between revisions)
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=== Ligand binding pocket === | === Ligand binding pocket === | ||
- | In the extracellular environement, there is a beta-hairpin in conjugaison with two extracellular disulfure bridges. This structure is responsible for the oppening and the locking of the ligand binding pocket <ref> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605637/ </ref>. The ligand go into an <scene name='82/829348/Ligand_blinding_pocket/1'>hydrophilic pocket</scene> created into the membrane thanks to the 7 alpha helix which creat gate between | + | In the extracellular environement, there is a beta-hairpin in conjugaison with two extracellular disulfure bridges. This structure is responsible for the oppening and the locking of the ligand binding pocket <ref> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605637/ </ref>. The ligand go into an <scene name='82/829348/Ligand_blinding_pocket/1'>hydrophilic pocket</scene> created into the membrane thanks to the 7 alpha helix which creat gate between the membrane and the extracellular environnement. |
=== G protein-binding site === | === G protein-binding site === | ||
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== References == | == References == | ||
<references/> | <references/> | ||
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- | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. |
Revision as of 14:14, 12 January 2020
This Sandbox is Reserved from 25/11/2019, through 30/9/2020 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1091 through Sandbox Reserved 1115. |
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Human Angiotensin Receptor
Angiotensin receptors belongs to the G protein coupled receptor (GPCR). It is a membrane protein located mainly in heart, brain, liver and kidneys.
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References
- ↑ https://www.researchgate.net/profile/Marc_De_Gasparo/publication/238340301_Les_rcepteurs_AT1_et_AT2_de_langiotensine_II_Lessentiel/links/567d3a9308aebccc4e03e6df.pdf
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705918/
- ↑ http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605637/
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457125/#!po=8.33333
- ↑ http://www.jbc.org/content/290/49/29127
- ↑ http://www.jbc.org/content/290/49/29127
- ↑ https://doi.org/10.1016/j.phrs.2017.06.013
- ↑ https://doi.org/10.1016/j.phrs.2017.06.013