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6jlq
From Proteopedia
(Difference between revisions)
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<StructureSection load='6jlq' size='340' side='right'caption='[[6jlq]], [[Resolution|resolution]] 3.10Å' scene=''> | <StructureSection load='6jlq' size='340' side='right'caption='[[6jlq]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6jlq]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6jlq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_mutus Bos mutus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JLQ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.101Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jlq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jlq OCA], [https://pdbe.org/6jlq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jlq RCSB], [https://www.ebi.ac.uk/pdbsum/6jlq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jlq ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | == Disease == | ||
| - | [[http://www.uniprot.org/uniprot/WDR48_HUMAN WDR48_HUMAN]] Autosomal recessive spastic paraplegia type 60. | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/UBP46_HUMAN UBP46_HUMAN] Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.<ref>PMID:19075014</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Thioesterase 3D structures|Thioesterase 3D structures]] | ||
| + | *[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bos mutus]] |
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Ding J]] | |
| - | [[Category: Ding | + | [[Category: Zhang T]] |
| - | [[Category: Zhang | + | [[Category: Zhu H]] |
| - | [[Category: Zhu | + | |
| - | + | ||
| - | + | ||
| - | + | ||
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Current revision
Crystal structure of human USP46-WDR48-WDR20 complex
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Categories: Bos mutus | Homo sapiens | Large Structures | Ding J | Zhang T | Zhu H
