1adu

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[[Image:1adu.gif|left|200px]]
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{{STRUCTURE_1adu| PDB=1adu | SCENE= }}
{{STRUCTURE_1adu| PDB=1adu | SCENE= }}
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'''EARLY E2A DNA-BINDING PROTEIN'''
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===EARLY E2A DNA-BINDING PROTEIN===
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==Overview==
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A second crystal form of the C-terminal domain of the adenovirus single-stranded DNA binding protein crystallizes in space group P2(1)2(1)2(1) with a=61.0 angstrom, b=91.2 angstrom and c=149.4 angstrom. The crystals contain two molecules per asymmetric unit and diffract to a maximum resolution of 3.0 angstrom. The crystal is composed of infinite chains of molecules along the crystallographic 2(1) axis parallel to c. The principal intermolecular interaction is a hooking of the C-terminal 17 residues of one molecule onto the next molecule in the protein chain. Adjacent molecules in the chain are rotated approximately 90 degrees with respect to their neighbours. The difference in relative orientation of adjacent molecules between the two crystal forms of the protein implies a degree of flexibility in the protein chain that would facilitate DNA binding.
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(as it appears on PubMed at http://www.pubmed.gov), where 8632448 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8632448}}
==About this Structure==
==About this Structure==
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[[Category: Dna-binding protein]]
[[Category: Dna-binding protein]]
[[Category: Ssdna binding protein]]
[[Category: Ssdna binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:38:25 2008''

Revision as of 13:38, 30 June 2008

Template:STRUCTURE 1adu

EARLY E2A DNA-BINDING PROTEIN

Template:ABSTRACT PUBMED 8632448

About this Structure

1ADU is a Single protein structure of sequence from Human adenovirus 5. Full crystallographic information is available from OCA.

Reference

Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein., Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA, J Mol Biol. 1996 Mar 22;257(1):1-8. PMID:8632448

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