6lk0

<table><tr><td colspan='2'>[[6lk0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LK0 FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRIP13, PCH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lk0 OCA], [http://pdbe.org/6lk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lk0 RCSB], [http://www.ebi.ac.uk/pdbsum/6lk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lk0 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PCH2_HUMAN PCH2_HUMAN]] Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity).

 

 

[[Category: Human]]

[[Category: Chang, S]]

[[Category: Chen, G]]

[[Category: Gao, L]]

[[Category: Hu, L]]

[[Category: Huang, J]]

[[Category: Kong, Y]]

[[Category: Li, B]]

[[Category: Lian, F]]

[[Category: Mao, Z]]

[[Category: Shi, J]]

[[Category: Sun, X]]

[[Category: Tao, Y]]

[[Category: Tricot, G]]

[[Category: Wang, Y]]

[[Category: Wu, X]]

[[Category: Xiao, W]]

[[Category: Xie, Y]]

[[Category: Xu, H]]

[[Category: Xu, Z]]

[[Category: Xue, H]]

[[Category: Yu, D]]

[[Category: Zhan, F]]

[[Category: Zhang, N]]

[[Category: Zhu, W]]

[[Category: Oncoprotein]]