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6tpg
From Proteopedia
(Difference between revisions)
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<StructureSection load='6tpg' size='340' side='right'caption='[[6tpg]], [[Resolution|resolution]] 2.74Å' scene=''> | <StructureSection load='6tpg' size='340' side='right'caption='[[6tpg]], [[Resolution|resolution]] 2.74Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6tpg]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6tpg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TPG FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7MA:N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide'>7MA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.741Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7MA:N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide'>7MA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tpg OCA], [https://pdbe.org/6tpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tpg RCSB], [https://www.ebi.ac.uk/pdbsum/6tpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tpg ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [https://www.uniprot.org/uniprot/Q9V2J8_PYRAB Q9V2J8_PYRAB] [https://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6tpg" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6tpg" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Ali | + | [[Category: Pyrococcus abyssi GE5]] |
| - | [[Category: Bennett | + | [[Category: Ali A]] |
| - | [[Category: Brown | + | [[Category: Bennett KA]] |
| - | [[Category: Bucknell | + | [[Category: Brown JD]] |
| - | [[Category: Christopher | + | [[Category: Bucknell SJ]] |
| - | [[Category: Congreve | + | [[Category: Christopher JA]] |
| - | [[Category: Cooke | + | [[Category: Congreve M]] |
| - | [[Category: Cseke | + | [[Category: Cooke RM]] |
| - | [[Category: Dore | + | [[Category: Cseke G]] |
| - | [[Category: Errey | + | [[Category: Dore AS]] |
| - | + | [[Category: Errey JC]] | |
| - | [[Category: Jazayeri | + | [[Category: Jazayeri A]] |
| - | [[Category: Marshall | + | [[Category: Marshall FH]] |
| - | [[Category: Mason | + | [[Category: Mason JS]] |
| - | [[Category: Mould | + | [[Category: Mould R]] |
| - | [[Category: Patel | + | [[Category: Patel JC]] |
| - | [[Category: Rappas | + | [[Category: Rappas M]] |
| - | [[Category: Tehan | + | [[Category: Tehan BG]] |
| - | [[Category: Weir | + | [[Category: Weir M]] |
| - | [[Category: | + | [[Category: De Graaf C]] |
| - | + | ||
Current revision
Crystal structure of the Orexin-2 receptor in complex with EMPA at 2.74 A resolution
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Categories: Homo sapiens | Large Structures | Pyrococcus abyssi GE5 | Ali A | Bennett KA | Brown JD | Bucknell SJ | Christopher JA | Congreve M | Cooke RM | Cseke G | Dore AS | Errey JC | Jazayeri A | Marshall FH | Mason JS | Mould R | Patel JC | Rappas M | Tehan BG | Weir M | De Graaf C
