4b87
From Proteopedia
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<StructureSection load='4b87' size='340' side='right'caption='[[4b87]], [[Resolution|resolution]] 2.16Å' scene=''> | <StructureSection load='4b87' size='340' side='right'caption='[[4b87]], [[Resolution|resolution]] 2.16Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4b87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B87 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4b87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B87 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b87 OCA], [https://pdbe.org/4b87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b87 RCSB], [https://www.ebi.ac.uk/pdbsum/4b87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b87 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 07:03, 31 August 2022
Crystal structure of human DNA cross-link repair 1A
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Categories: Large Structures | Allerston, C K | Arrowsmith, C H | Berridge, G | Bountra, C | Carpenter, E P | Delft, F von | Edwards, A | Gileadi, O | Kochan, G | Krojer, T | Mahajan, P | Vollmar, M | Yue, W W | Cancer | Chemotherapy | Dclre | Dclre1a | Hydrolase | Interstrand crosslink repair | Nitrogen mustard | Pso2 homolog
