6vip

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:13, 11 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6vip' size='340' side='right'caption='[[6vip]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
<StructureSection load='6vip' size='340' side='right'caption='[[6vip]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6vip]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VIP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VIP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6vip]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VIP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QXY:{4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]phenyl}(4-ethylpiperazin-1-yl)methanone'>QXY</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.36&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vip OCA], [http://pdbe.org/6vip PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vip RCSB], [http://www.ebi.ac.uk/pdbsum/6vip PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vip ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QXY:{4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]phenyl}(4-ethylpiperazin-1-yl)methanone'>QXY</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vip OCA], [https://pdbe.org/6vip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vip RCSB], [https://www.ebi.ac.uk/pdbsum/6vip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vip ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.
+
[https://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref> <ref>PMID:17190600</ref>
+
[https://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref> <ref>PMID:17190600</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bountra, C]]
+
[[Category: Bountra C]]
-
[[Category: Brown, P J]]
+
[[Category: Brown PJ]]
-
[[Category: Doak, B]]
+
[[Category: Doak B]]
-
[[Category: Dong, A]]
+
[[Category: Dong A]]
-
[[Category: Edwards, A M]]
+
[[Category: Edwards AM]]
-
[[Category: Gunzburg, M]]
+
[[Category: Gunzburg M]]
-
[[Category: Headey, S]]
+
[[Category: Headey S]]
-
[[Category: Hong, Z]]
+
[[Category: Hong Z]]
-
[[Category: James, L I]]
+
[[Category: James LI]]
-
[[Category: Structural genomic]]
+
[[Category: The J]]
-
[[Category: The, J]]
+
-
[[Category: Mfp-6008]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Sgc]]
+
-
[[Category: Transcription]]
+
-
[[Category: Tudor]]
+

Current revision

TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-6008

PDB ID 6vip

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6vip"
Personal tools