6knm

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Current revision (10:37, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6knm' size='340' side='right'caption='[[6knm]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='6knm' size='340' side='right'caption='[[6knm]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6knm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pasteurianus"_(winogradsky_1895)_lehmann_and_neumann_1907 "bacillus pasteurianus" (winogradsky 1895) lehmann and neumann 1907] and [http://en.wikipedia.org/wiki/Bactrian_camel Bactrian camel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KNM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KNM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6knm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_bactrianus Camelus bactrianus], [https://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KNM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APLNR, AGTRL1, APJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1501 "Bacillus pasteurianus" (Winogradsky 1895) Lehmann and Neumann 1907])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6knm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6knm OCA], [http://pdbe.org/6knm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6knm RCSB], [http://www.ebi.ac.uk/pdbsum/6knm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6knm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6knm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6knm OCA], [https://pdbe.org/6knm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6knm RCSB], [https://www.ebi.ac.uk/pdbsum/6knm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6knm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/APJ_HUMAN APJ_HUMAN]] Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
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[https://www.uniprot.org/uniprot/APJ_HUMAN APJ_HUMAN] Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.[https://www.uniprot.org/uniprot/RUBR_CLOPA RUBR_CLOPA] Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6knm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6knm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bactrian camel]]
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[[Category: Camelus bactrianus]]
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[[Category: Clostridium pasteurianum]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ding, Y]]
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[[Category: Ding Y]]
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[[Category: Hu, L A]]
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[[Category: Hu LA]]
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[[Category: Li, X]]
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[[Category: Li X]]
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[[Category: Ma, X]]
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[[Category: Ma X]]
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[[Category: Ma, Y B]]
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[[Category: Ma YB]]
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[[Category: Ma, Y L]]
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[[Category: Ma YL]]
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[[Category: Shen, Y]]
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[[Category: Shen Y]]
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[[Category: Song, X]]
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[[Category: Song X]]
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[[Category: Song, Y]]
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[[Category: Song Y]]
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[[Category: Sun, Y]]
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[[Category: Sun Y]]
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[[Category: Zhang, M Y]]
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[[Category: Zhang MY]]
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[[Category: Zhang, N]]
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[[Category: Zhang N]]
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[[Category: Zhong, W]]
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[[Category: Zhong W]]
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[[Category: Agonist]]
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[[Category: Antagonist]]
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[[Category: Gpcr]]
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[[Category: Membrane protein]]
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[[Category: Single-domain antibody]]
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Current revision

Apelin receptor in complex with single domain antibody

PDB ID 6knm

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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