Talin
From Proteopedia
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| - | <StructureSection load='' size='350' side='right' scene='Talin/Cv/1' caption='Talin residues 1359-1659 (PDB code [[2x0c]])'> | + | <StructureSection load='' size='350' side='right' scene='Talin/Cv/1' caption='Talin rod domain residues 1359-1659 (PDB code [[2x0c]])'> |
[[Talin]] is involved in cell-cell contacts. It links integrins to actin<ref>PMID:19416068</ref>. It contains a C-terminal rod domain with integrin binding sites (IBS) and actin binding sites (ABS) and N-terminal FERM domain with subdomains F1-F3. The F3 subdomain interacts with integrin. Talin contains 3 [[Vinculin]] binding sites VBS1-VBS3. | [[Talin]] is involved in cell-cell contacts. It links integrins to actin<ref>PMID:19416068</ref>. It contains a C-terminal rod domain with integrin binding sites (IBS) and actin binding sites (ABS) and N-terminal FERM domain with subdomains F1-F3. The F3 subdomain interacts with integrin. Talin contains 3 [[Vinculin]] binding sites VBS1-VBS3. | ||
Revision as of 07:42, 13 February 2020
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3D Structures of Talin
Updated on 13-February-2020
References
- ↑ Critchley DR. Biochemical and structural properties of the integrin-associated cytoskeletal protein talin. Annu Rev Biophys. 2009;38:235-54. doi: 10.1146/annurev.biophys.050708.133744. PMID:19416068 doi:http://dx.doi.org/10.1146/annurev.biophys.050708.133744
