Tetracycline repressor protein

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== 3D Structures of tetracycline repressor protein==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Tetracycline repressor protein class A
 
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**[[5mru]] – TetR + Mg + anhydro-TC - ''Pseudomonas''<br />
 
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*Tetracycline repressor protein class B
 
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**[[3fk6]] - EcTetR (mutant) <br />
 
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**[[3fk7]] - EcTetR (mutant) + Mg + 4-DDMA-ATC<br />
 
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**[[3zqf]], [[3zqg]], [[3zqh]], [[3zqi]] – EcTetR (mutant) + anti-inducer peptide<br />
 
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**[[2vkv]] – EcTetR (mutant) + Mg + anhydro-TC<br />
 
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**[[4ac0]] – EcTetR + Mg + minocycline<br />
 
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**[[6sy4]], [[6sy6]] – EcTetR B + Mg + RNA<br />
 
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*Tetracycline repressor protein class D
 
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**[[4v2f]] – EcTetR D - ''Escherichia coli'' <br />
 
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**[[1bjz]], [[1a6i]], [[2ns7]], [[2xgc]], [[2xgd]], [[2xge]], [[6fts]] - EcTetR (mutant) <br />
 
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**[[1qpi]] – EcTetR + DNA<br />
 
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*Tetracycline repressor protein class D complex with tetracycline and tetracycline derivative
 
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**[[2tct]] – EcTetR + Mg + chloro-TC<br />
 
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**[[4v2g]] – EcTetR + Mg + chloro-TC + iso- chloro-TC <br />
 
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**[[2trt]] – EcTetR + Mg + TC<br />
 
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**[[4b3a]] – EcTetR (mutant) + Mg + TC<br />
 
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**[[2x9d]], [[4b1r]] – EcTetR (mutant) + chloro-TC<br />
 
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**[[1ork]], [[5fkk]], [[5fkl]], [[5fkm]], [[5fkn]], [[5fko]], [[6fpl]], [[6fpm]], [[6qjw]] - EcTetR (mutant) + Mg + TC derivative<br />
 
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**[[2fj1]] – EcTetR (mutant) + Ni + chloro-TC<br />
 
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**[[2o7o]], [[2xrl]], [[6rbl]], [[6rcr]], [[6rgx]] – EcTetR (mutant) + Mg + doxy-TC<br />
 
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**[[2ns8]] – EcTetR (mutant) + Mg + TC peptide mimic<br />
 
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**[[2vke]] – EcTetR + Co + TC<br />
 
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**[[4d7m]] – EcTetR + Mg + anhydro-TC<br />
 
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**[[4d7n]] – EcTetR + K + anhydro-TC<br />
 
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**[[2xpu]] – EcTetR + anhydro-TC<br />
 
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**[[2xb5]] – EcTetR + Mg + iodo-TC<br />
 
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**[[2xpv]] – EcTetR + Mg + minocycline<br />
 
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**[[6qjx]], [[6rbm]] – EcTetR D (mutant) + Mg + minocycline<br />
 
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**[[4abz]] – EcTetR + Mg + tigecycline<br />
 
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**[[2xpw]] – EcTetR + Mg + oxy-TC<br />
 
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**[[4aux]] – EcTetR + Mg + nitro-TC<br />
 
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**[[2x6o]] – EcTetR + TC derivative<br />
 
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*TetR class J
 
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**[[4d5c]] – TetR J – ''Proteus mirabilis''<br />
 
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*TetR class H
 
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**[[4d5f]] – TetR H – ''Mannheimia haemolytica''<br />
 
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*TetR family (transcriptional regulator)
 
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**[[1z0x]] – TetR – ''Enterococcus faecalis''<br />
 
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**[[1z77]], [[1zkg]], [[2id6]] – TetR – ''Thermotoga maritima''<br />
 
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**[[1zk8]], [[2fq4]] – TetR – ''Bacillus cereus''<br />
 
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**[[2g7s]] – TetR – ''Agrobacterium tumefaciens''<br />
 
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**[[2hyt]] – TetR – ''Pectobacterium atrosepticum''<br />
 
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**[[2qtq]] – TetR – ''Sphingobium aromaticivorans''<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:45, 16 February 2020

Tetracycline repressor protein complex with tetracycline and Mg+2 ion (green), 2trt

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References

  1. Bertram R, Hillen W. The application of Tet repressor in prokaryotic gene regulation and expression. Microb Biotechnol. 2008 Jan;1(1):2-16. doi: 10.1111/j.1751-7915.2007.00001.x. PMID:21261817 doi:http://dx.doi.org/10.1111/j.1751-7915.2007.00001.x
  2. Hinrichs W, Kisker C, Duvel M, Muller A, Tovar K, Hillen W, Saenger W. Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance. Science. 1994 Apr 15;264(5157):418-20. PMID:8153629

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Michal Harel, Alexander Berchansky

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