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6vtk
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH== | |
| - | + | <StructureSection load='6vtk' size='340' side='right'caption='[[6vtk]], [[Resolution|resolution]] 2.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6vtk]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VTK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VTK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vtk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vtk OCA], [http://pdbe.org/6vtk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vtk RCSB], [http://www.ebi.ac.uk/pdbsum/6vtk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vtk ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ASIC1_CHICK ASIC1_CHICK]] Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride (By similarity).<ref>PMID:16002453</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gouaux, E]] | ||
| + | [[Category: Yoder, N]] | ||
| + | [[Category: Acid-sensing ion channel]] | ||
| + | [[Category: Asic]] | ||
| + | [[Category: Asic1a]] | ||
| + | [[Category: Ion channel]] | ||
| + | [[Category: Ligand-gated ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Proton-gated ion channel]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 07:33, 11 March 2020
Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH
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