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6tr7

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Current revision (13:07, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6tr7' size='340' side='right'caption='[[6tr7]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
<StructureSection load='6tr7' size='340' side='right'caption='[[6tr7]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6tr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TR7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6tr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TR7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HWH:~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide'>HWH</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NOTUM, OK/SW-CL.30 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HWH:~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide'>HWH</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Wnt_protein]_O-palmitoleoyl-L-serine_hydrolase [Wnt protein] O-palmitoleoyl-L-serine hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.98 3.1.1.98] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tr7 OCA], [https://pdbe.org/6tr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tr7 RCSB], [https://www.ebi.ac.uk/pdbsum/6tr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tr7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tr7 OCA], [http://pdbe.org/6tr7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tr7 RCSB], [http://www.ebi.ac.uk/pdbsum/6tr7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tr7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NOTUM_HUMAN NOTUM_HUMAN]] May deacetylate GlcNAc residues on cell surface glycans.
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[https://www.uniprot.org/uniprot/NOTUM_HUMAN NOTUM_HUMAN] May deacetylate GlcNAc residues on cell surface glycans.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jones, E Y]]
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[[Category: Jones EY]]
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[[Category: Zhao, Y]]
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[[Category: Zhao Y]]
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[[Category: Oncoprotein]]
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[[Category: Wnt receptor frizzled8 carbamazepine]]
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Current revision

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide-Notum complex

PDB ID 6tr7

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