1ajv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ajv.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1ajv.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ajv| PDB=1ajv | SCENE= }}
{{STRUCTURE_1ajv| PDB=1ajv | SCENE= }}
-
'''HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC SULFAMIDE INHIBITOR AHA006'''
+
===HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC SULFAMIDE INHIBITOR AHA006===
-
==Overview==
+
<!--
-
Two cyclic, C2-symmetric HIV-1 protease inhibitors, one sulfamide and one urea derivative, both comprising phenyl ether groups in the P1/P1' positions, were cocrystallized with HIV-1 protease, and the crystal structures were determined to 2.0 A resolution. The structure of the urea 2 showed a conformation similar to that reported for the related urea 3 by Lam et al., while the sulfamide 1 adopted an unanticipated conformation in which the P1' and P2' side chains were transposed.
+
The line below this paragraph, {{ABSTRACT_PUBMED_9083478}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 9083478 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_9083478}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Non-peptide inhibitor]]
[[Category: Non-peptide inhibitor]]
[[Category: Protease]]
[[Category: Protease]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:21:56 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:00:14 2008''

Revision as of 14:00, 30 June 2008

Image:1ajv.png

Template:STRUCTURE 1ajv

HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC SULFAMIDE INHIBITOR AHA006

Template:ABSTRACT PUBMED 9083478

About this Structure

1AJV is a Single protein structure of sequence from Human immunodeficiency virus type 1 (isolate 12). Full crystallographic information is available from OCA.

Reference

Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor., Backbro K, Lowgren S, Osterlund K, Atepo J, Unge T, Hulten J, Bonham NM, Schaal W, Karlen A, Hallberg A, J Med Chem. 1997 Mar 14;40(6):898-902. PMID:9083478

Page seeded by OCA on Mon Jun 30 17:00:14 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ajv"
Personal tools