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6qmf

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<StructureSection load='6qmf' size='340' side='right'caption='[[6qmf]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='6qmf' size='340' side='right'caption='[[6qmf]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6qmf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QMF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6qmf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6g7u 6g7u]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QMF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QMF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EQ5:3-indol-1-ylpropanoic+acid'>EQ5</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EQ5:3-indol-1-ylpropanoic+acid'>EQ5</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qmf OCA], [https://pdbe.org/6qmf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qmf RCSB], [https://www.ebi.ac.uk/pdbsum/6qmf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qmf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qmf OCA], [http://pdbe.org/6qmf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qmf RCSB], [http://www.ebi.ac.uk/pdbsum/6qmf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qmf ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
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[https://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pantetheine-phosphate adenylyltransferase]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Blaszczyk, M]]
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[[Category: Blaszczyk M]]
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[[Category: Blundell, T L]]
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[[Category: Blundell TL]]
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[[Category: Coad]]
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[[Category: Complex]]
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[[Category: Ppat]]
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[[Category: Transferase]]
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Revision as of 10:17, 15 February 2023

Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 5-[3-(1H-indol-3-yl)propoxy]-1-phenyl-1H-pyrazole-4-carboxylic acid at 1.8A resolution.

PDB ID 6qmf

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