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2klc
From Proteopedia
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<StructureSection load='2klc' size='340' side='right'caption='[[2klc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2klc' size='340' side='right'caption='[[2klc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLC FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DA41, PLIC1, UBQLN1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DA41, PLIC1, UBQLN1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [https://pdbe.org/2klc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [https://www.ebi.ac.uk/pdbsum/2klc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:07, 1 December 2021
NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A
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Categories: Human | Large Structures | Arrowsmith, C H | Dhe-Paganon, S | Doherty, R S | Fares, C | Garcia, M | Gutmanas, A | Lemak, S | Montelione, G T | Structural genomic | OCSP, Ontario Centre for Structural Proteomics | Yee, A | Alzheimerss' | Nesg | Nucleus | Ocsp | Ontario centre for structural proteomic | Phosphoprotein | Proteasome | Protein binding | Protein degradation | PSI, Protein structure initiative | Sgc | Ubiquitin ligase-associated | Ubiquitin-like | Ubiquitination | Ubl | Unknown function

