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2cre
From Proteopedia
(Difference between revisions)
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<StructureSection load='2cre' size='340' side='right'caption='[[2cre]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2cre' size='340' side='right'caption='[[2cre]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2cre]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2cre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CRE FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cre OCA], [https://pdbe.org/2cre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cre RCSB], [https://www.ebi.ac.uk/pdbsum/2cre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cre ProSAT], [https://www.topsan.org/Proteins/RSGI/2cre TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CASS4_HUMAN CASS4_HUMAN]] Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading.<ref>PMID:18256281</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:00, 1 December 2021
Solution structure of RSGI RUH-036, an SH3 domain from human cDNA
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