This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4uco
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4uco' size='340' side='right'caption='[[4uco]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4uco' size='340' side='right'caption='[[4uco]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4uco]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4uco]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCO FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D41:7-AMINO-2-TERT-BUTYL-4-(1H-PYRROL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>D41</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D41:7-AMINO-2-TERT-BUTYL-4-(1H-PYRROL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>D41</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uco OCA], [https://pdbe.org/4uco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uco RCSB], [https://www.ebi.ac.uk/pdbsum/4uco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uco ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). |
==See Also== | ==See Also== | ||
| Line 16: | Line 14: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Haemophilus influenzae]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Boriack-Sjodin | + | [[Category: Boriack-Sjodin PA]] |
| - | [[Category: Brassington | + | [[Category: Brassington C]] |
| - | [[Category: Carcanague | + | [[Category: Carcanague D]] |
| - | [[Category: Embrey | + | [[Category: Embrey K]] |
| - | [[Category: Eyermann | + | [[Category: Eyermann CJ]] |
| - | [[Category: Giacobbe | + | [[Category: Giacobbe RA]] |
| - | [[Category: Gingipali | + | [[Category: Gingipali L]] |
| - | [[Category: Gowravaram | + | [[Category: Gowravaram M]] |
| - | [[Category: Hale | + | [[Category: Hale M]] |
| - | [[Category: Harang | + | [[Category: Harang J]] |
| - | [[Category: Howard | + | [[Category: Howard T]] |
| - | [[Category: Ioannidis | + | [[Category: Ioannidis G]] |
| - | [[Category: Jahic | + | [[Category: Jahic H]] |
| - | [[Category: Kutschke | + | [[Category: Kutschke A]] |
| - | [[Category: Laganas | + | [[Category: Laganas VA]] |
| - | [[Category: Loch | + | [[Category: Loch J]] |
| - | [[Category: Miller | + | [[Category: Miller MD]] |
| - | [[Category: Murphy-Benenato | + | [[Category: Murphy-Benenato KE]] |
| - | [[Category: Oguto | + | [[Category: Oguto H]] |
| - | [[Category: Otterbein | + | [[Category: Otterbein L]] |
| - | [[Category: Patel | + | [[Category: Patel SJ]] |
| - | [[Category: Shapiro | + | [[Category: Shapiro AB]] |
| - | + | ||
Revision as of 08:15, 22 March 2023
Fragment bound to H.influenza NAD dependent DNA ligase
| |||||||||||
Categories: Haemophilus influenzae | Large Structures | Boriack-Sjodin PA | Brassington C | Carcanague D | Embrey K | Eyermann CJ | Giacobbe RA | Gingipali L | Gowravaram M | Hale M | Harang J | Howard T | Ioannidis G | Jahic H | Kutschke A | Laganas VA | Loch J | Miller MD | Murphy-Benenato KE | Oguto H | Otterbein L | Patel SJ | Shapiro AB
