6y6f
From Proteopedia
(Difference between revisions)
m (Protected "6y6f" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of STK17B (DRAK2) in complex with PKIS43== | |
| - | + | <StructureSection load='6y6f' size='340' side='right'caption='[[6y6f]], [[Resolution|resolution]] 1.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6y6f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y6F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OD2:2-[6-(4-methylsulfanylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic+acid'>OD2</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6f OCA], [http://pdbe.org/6y6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y6f RCSB], [http://www.ebi.ac.uk/pdbsum/6y6f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6f ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
[[Category: Chaikuad, A]] | [[Category: Chaikuad, A]] | ||
| - | [[Category: | + | [[Category: Drewry, D]] |
| + | [[Category: Edwards, A M]] | ||
[[Category: Knapp, S]] | [[Category: Knapp, S]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Chemical probe]] |
| - | [[Category: | + | [[Category: Drak2]] |
| - | [[Category: | + | [[Category: Kinase]] |
| + | [[Category: Kinase inhibitor]] | ||
| + | [[Category: Pki]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 07:34, 11 March 2020
Crystal structure of STK17B (DRAK2) in complex with PKIS43
| |||||||||||
