6y6h

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m (Protected "6y6h" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6y6h is ON HOLD
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==Crystal structure of STK17b (DRAK2) in complex with UNC-AP-194 probe==
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<StructureSection load='6y6h' size='340' side='right'caption='[[6y6h]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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Authors: Chaikuad, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Drewry, D., Knapp, S., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6y6h]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y6H FirstGlance]. <br>
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Description: Crystal structure of STK17b (DRAK2) in complex with UNC-AP-194 probe
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OBW:2-[6-(1-benzothiophen-2-yl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic+acid'>OBW</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6h OCA], [http://pdbe.org/6y6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y6h RCSB], [http://www.ebi.ac.uk/pdbsum/6y6h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
[[Category: Chaikuad, A]]
[[Category: Chaikuad, A]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Drewry, D]]
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[[Category: Edwards, A M]]
[[Category: Knapp, S]]
[[Category: Knapp, S]]
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[[Category: Drewry, D]]
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[[Category: Structural genomic]]
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[[Category: Edwards, A.M]]
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[[Category: Chemical probe]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Drak2]]
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[[Category: Bountra, C]]
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[[Category: Kinase]]
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[[Category: Kinase inhibitor]]
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[[Category: Pki]]
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[[Category: Sgc]]
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[[Category: Transferase]]

Revision as of 07:34, 11 March 2020

Crystal structure of STK17b (DRAK2) in complex with UNC-AP-194 probe

PDB ID 6y6h

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