3foh

From Proteopedia

(Difference between revisions)

Revision as of 17:21, 10 April 2020

Fitting of gp18M crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 extended tail

3foh, resolution 15.00Å

Structural highlights

3foh is a 6 chain structure with sequence from Bpt4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	3foa, 3fo8, 3foi
Gene:	18, GB AAA32541 (BPT4)
Experimental data:	Check to display Experimental Data
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[VG18_BPT4] The contractile tail of bacteriophage T4 consists of a contractile sheath, a tube and a baseplate. 144 protomers of Gp18, arranged in 24 annuli, form the contractile tail sheath which participates in viral DNA injection into host cytoplasm.

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The contractile tail of bacteriophage T4 is a molecular machine that facilitates very high viral infection efficiency. Its major component is a tail sheath, which contracts during infection to less than half of its initial length. The sheath consists of 138 copies of the tail sheath protein, gene product (gp) 18, which surrounds the central non-contractile tail tube. The contraction of the sheath drives the tail tube through the outer membrane, creating a channel for the viral genome delivery. A crystal structure of about three quarters of gp18 has been determined and was fitted into cryo-electron microscopy reconstructions of the tail sheath before and after contraction. It was shown that during contraction, gp18 subunits slide over each other with no apparent change in their structure.

The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.,Aksyuk AA, Leiman PG, Kurochkina LP, Shneider MM, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG EMBO J. 2009 Apr 8;28(7):821-9. Epub 2009 Feb 19. PMID:19229296^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Aksyuk AA, Leiman PG, Kurochkina LP, Shneider MM, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG. The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria. EMBO J. 2009 Apr 8;28(7):821-9. Epub 2009 Feb 19. PMID:19229296 doi:http://dx.doi.org/10.1038/emboj.2009.36

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3foh"

@@ Line 3: / Line 3: @@
 <SX load='3foh' size='340' side='right' viewer='molstar' caption='[[3foh]], [[Resolution|resolution]] 15.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3foh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FOH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FOH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3foh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FOH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3FOH FirstGlance]. <br>
 </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3foa|3foa]], [[3fo8|3fo8]], [[3foi|3foi]]</td></tr>
 <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3foh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3foh OCA], [http://pdbe.org/3foh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3foh RCSB], [http://www.ebi.ac.uk/pdbsum/3foh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3foh ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3foh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3foh OCA], [http://pdbe.org/3foh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3foh RCSB], [http://www.ebi.ac.uk/pdbsum/3foh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3foh ProSAT]</span></td></tr>
 </table>
 == Function ==

3foh

From Proteopedia

Revision as of 17:21, 10 April 2020

Fitting of gp18M crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 extended tail

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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