1ao6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ao6.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1ao6.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ao6| PDB=1ao6 | SCENE= }}
{{STRUCTURE_1ao6| PDB=1ao6 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN'''
+
===CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN===
-
==Overview==
+
<!--
-
A new triclinic crystal form of human serum albumin (HSA), derived either from pool plasma (pHSA) or from a Pichia pastoris expression system (rHSA), was obtained from polyethylene glycol 4000 solution. Three-dimensional structures of pHSA and rHSA were determined at 2.5 A resolution from the new triclinic crystal form by molecular replacement, using atomic coordinates derived from a multiple isomorphous replacement work with a known tetragonal crystal form. The structures of pHSA and rHSA are virtually identical, with an r.m. s. deviation of 0.24 A for all Calpha atoms. The two HSA molecules involved in the asymmetric unit are related by a strict local twofold symmetry such that the Calpha atoms of the two molecules can be superimposed with an r.m.s. deviation of 0.28 A in pHSA. Cys34 is the only cysteine with a free sulfhydryl group which does not participate in a disulfide linkage with any external ligand. Domains II and III both have a pocket formed mostly of hydrophobic and positively charged residues and in which a very wide range of compounds may be accommodated. Three tentative binding sites for long-chain fatty acids, each with different surroundings, are located at the surface of each domain.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10388840}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10388840 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10388840}}
==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Albumin]]
[[Category: Albumin]]
[[Category: Carrier protein]]
[[Category: Carrier protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:30:11 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:16:26 2008''

Revision as of 14:16, 30 June 2008

Image:1ao6.png

Template:STRUCTURE 1ao6

CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN

Template:ABSTRACT PUBMED 10388840

About this Structure

1AO6 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human serum albumin at 2.5 A resolution., Sugio S, Kashima A, Mochizuki S, Noda M, Kobayashi K, Protein Eng. 1999 Jun;12(6):439-46. PMID:10388840

Page seeded by OCA on Mon Jun 30 17:16:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ao6"
Personal tools