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5irx

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<SX load='5irx' size='340' side='right' viewer='molstar' caption='[[5irx]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
<SX load='5irx' size='340' side='right' viewer='molstar' caption='[[5irx]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5irx]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Cyrsc Cyrsc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IRX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IRX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5irx]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Cyrsc Cyrsc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IRX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IRX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6EU:RESINIFERATOXIN'>6EU</scene>, <scene name='pdbligand=6O8:(4R,7S)-4-HYDROXY-N,N,N-TRIMETHYL-4,9-DIOXO-7-[(PENTANOYLOXY)METHYL]-3,5,8-TRIOXA-4LAMBDA~5~-PHOSPHATETRADECAN-1-AMINIUM'>6O8</scene>, <scene name='pdbligand=6O9:(2S)-2-(ACETYLOXY)-3-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}PROPYL+PENTANOATE'>6O9</scene>, <scene name='pdbligand=6OE:(2S)-3-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-2-(HEXANOYLOXY)PROPYL+HEXANOATE'>6OE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6EU:RESINIFERATOXIN'>6EU</scene>, <scene name='pdbligand=6O8:(4R,7S)-4-HYDROXY-N,N,N-TRIMETHYL-4,9-DIOXO-7-[(PENTANOYLOXY)METHYL]-3,5,8-TRIOXA-4LAMBDA~5~-PHOSPHATETRADECAN-1-AMINIUM'>6O8</scene>, <scene name='pdbligand=6O9:(2S)-2-(ACETYLOXY)-3-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}PROPYL+PENTANOATE'>6O9</scene>, <scene name='pdbligand=6OE:(2S)-3-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-2-(HEXANOYLOXY)PROPYL+HEXANOATE'>6OE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5irz|5irz]], [[5is0|5is0]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5irz|5irz]], [[5is0|5is0]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Trpv1, Vr1, Vr1l ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Trpv1, Vr1, Vr1l ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5irx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5irx OCA], [http://pdbe.org/5irx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5irx RCSB], [http://www.ebi.ac.uk/pdbsum/5irx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5irx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5irx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5irx OCA], [http://pdbe.org/5irx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5irx RCSB], [http://www.ebi.ac.uk/pdbsum/5irx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5irx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 20:17, 10 April 2020

Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc

5irx, resolution 2.95Å

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