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6nq2

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Current revision (03:29, 11 April 2020) (edit) (undo)
 
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<SX load='6nq2' size='340' side='right' viewer='molstar' caption='[[6nq2]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<SX load='6nq2' size='340' side='right' viewer='molstar' caption='[[6nq2]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6nq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NQ2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6nq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6NQ2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EUJ:(2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl+dioctanoate'>EUJ</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EUJ:(2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl+dioctanoate'>EUJ</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPCN2, TPC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPCN2, TPC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nq2 OCA], [http://pdbe.org/6nq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nq2 RCSB], [http://www.ebi.ac.uk/pdbsum/6nq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nq2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6nq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nq2 OCA], [http://pdbe.org/6nq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nq2 RCSB], [http://www.ebi.ac.uk/pdbsum/6nq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nq2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Current revision

Cryo-EM structure of human TPC2 channel in the ligand-bound closed state

6nq2, resolution 3.40Å

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OCA

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