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6nwa

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Revision as of 03:35, 11 April 2020

The structure of the photosystem I IsiA super-complex

6nwa, resolution 3.48Å

Structural highlights

6nwa is a 51 chain structure with sequence from Synechocystis sp. pcc 6803. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:	Photosystem I, with EC number 1.97.1.12
Experimental data:	Check to display Experimental Data
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ISIA_SYNY3] Functions as an antenna for photosystem I (PSI) under iron-limiting conditions, when phycobilisomes disappear. In the (PSI)3(Isi3)18 complex most of the harvested energy is probably used by PSI; in other PSI-containing supercomplexes a large part of the energy will probably not be used for light harvesting, but rather is dissipated to protect the organism from light damage.^[1] ^[2] [PSAE_SYNY3] Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.[HAMAP-Rule:MF_00613]

Publication Abstract from PubMed

Photochemical conversion in oxygenic photosynthesis takes place in two large protein-pigment complexes named photosystem II and photosystem I (PSII and PSI, respectively). Photosystems associate with antennae in vivo to increase the size of photosynthetic units to hundreds or thousands of pigments. Regulation of the interactions between antennae and photosystems allows photosynthetic organisms to adapt to their environment. In low-iron environments, cyanobacteria express IsiA, a PSI antenna, critical to their survival. Here we describe the structure of the PSI-IsiA complex isolated from the mesophilic cyanobacterium Synechocystis sp. PCC 6803. This 2-MDa photosystem-antenna supercomplex structure reveals more than 700 pigments coordinated by 51 subunits, as well as the mechanisms facilitating the self-assembly and association of IsiA with multiple PSI assemblies.

The structure of the stress-induced photosystem I-IsiA antenna supercomplex.,Toporik H, Li J, Williams D, Chiu PL, Mazor Y Nat Struct Mol Biol. 2019 Jun;26(6):443-449. doi: 10.1038/s41594-019-0228-8. Epub, 2019 May 27. PMID:31133699^[3]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Bibby TS, Nield J, Barber J. Iron deficiency induces the formation of an antenna ring around trimeric photosystem I in cyanobacteria. Nature. 2001 Aug 16;412(6848):743-5. PMID:11507643 doi:http://dx.doi.org/10.1038/35089098
↑ Ihalainen JA, D'Haene S, Yeremenko N, van Roon H, Arteni AA, Boekema EJ, van Grondelle R, Matthijs HC, Dekker JP. Aggregates of the chlorophyll-binding protein IsiA (CP43') dissipate energy in cyanobacteria. Biochemistry. 2005 Aug 16;44(32):10846-53. PMID:16086587 doi:http://dx.doi.org/10.1021/bi0510680
↑ Toporik H, Li J, Williams D, Chiu PL, Mazor Y. The structure of the stress-induced photosystem I-IsiA antenna supercomplex. Nat Struct Mol Biol. 2019 Jun;26(6):443-449. doi: 10.1038/s41594-019-0228-8. Epub, 2019 May 27. PMID:31133699 doi:http://dx.doi.org/10.1038/s41594-019-0228-8

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6nwa"

@@ Line 3: / Line 3: @@
 <SX load='6nwa' size='340' side='right' viewer='molstar' caption='[[6nwa]], [[Resolution|resolution]] 3.48&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6nwa]] is a 51 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NWA FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6nwa]] is a 51 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6NWA FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCR:BETA-CAROTENE'>BCR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL0:CHLOROPHYLL+A+ISOMER'>CL0</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene>, <scene name='pdbligand=LMG:1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE'>LMG</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PQN:PHYLLOQUINONE'>PQN</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCR:BETA-CAROTENE'>BCR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL0:CHLOROPHYLL+A+ISOMER'>CL0</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene>, <scene name='pdbligand=LMG:1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE'>LMG</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PQN:PHYLLOQUINONE'>PQN</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Photosystem_I Photosystem I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.97.1.12 1.97.1.12] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwa OCA], [http://pdbe.org/6nwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nwa RCSB], [http://www.ebi.ac.uk/pdbsum/6nwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwa ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6nwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwa OCA], [http://pdbe.org/6nwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nwa RCSB], [http://www.ebi.ac.uk/pdbsum/6nwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwa ProSAT]</span></td></tr>
 </table>
 == Function ==

6nwa

From Proteopedia

Revision as of 03:35, 11 April 2020

The structure of the photosystem I IsiA super-complex

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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