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6puu

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<SX load='6puu' size='340' side='right' viewer='molstar' caption='[[6puu]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
<SX load='6puu' size='340' side='right' viewer='molstar' caption='[[6puu]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6puu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PUU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PUU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6puu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PUU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6PUU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CV1:(2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate+8,10-dioxide'>CV1</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CV1:(2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate+8,10-dioxide'>CV1</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRPM2, EREG1, KNP3, LTRPC2, TRPC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRPM2, EREG1, KNP3, LTRPC2, TRPC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6puu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6puu OCA], [http://pdbe.org/6puu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6puu RCSB], [http://www.ebi.ac.uk/pdbsum/6puu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6puu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6puu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6puu OCA], [http://pdbe.org/6puu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6puu RCSB], [http://www.ebi.ac.uk/pdbsum/6puu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6puu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 04:37, 11 April 2020

Human TRPM2 bound to 8-Br-cADPR and calcium

6puu, resolution 3.70Å

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