This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

6rjh

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Revision as of 05:44, 11 April 2020

3D structure of horse spleen apoferritin determined using multifunctional graphene supports for electron cryomicroscopy

6rjh, resolution 2.00Å

Structural highlights

6rjh is a 24 chain structure with sequence from Equus caballus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Experimental data:	Check to display Experimental Data
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[FRIL_HORSE] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

Publication Abstract from PubMed

With recent technological advances, the atomic resolution structure of any purified biomolecular complex can, in principle, be determined by single-particle electron cryomicroscopy (cryoEM). In practice, the primary barrier to structure determination is the preparation of a frozen specimen suitable for high-resolution imaging. To address this, we present a multifunctional specimen support for cryoEM, comprising large-crystal monolayer graphene suspended across the surface of an ultrastable gold specimen support. Using a low-energy plasma surface modification system, we tune the surface of this support to the specimen by patterning a range of covalent functionalizations across the graphene layer on a single grid. This support design reduces specimen movement during imaging, improves image quality, and allows high-resolution structure determination with a minimum of material and data.

Multifunctional graphene supports for electron cryomicroscopy.,Naydenova K, Peet MJ, Russo CJ Proc Natl Acad Sci U S A. 2019 May 24. pii: 1904766116. doi:, 10.1073/pnas.1904766116. PMID:31127045^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Naydenova K, Peet MJ, Russo CJ. Multifunctional graphene supports for electron cryomicroscopy. Proc Natl Acad Sci U S A. 2019 May 24. pii: 1904766116. doi:, 10.1073/pnas.1904766116. PMID:31127045 doi:http://dx.doi.org/10.1073/pnas.1904766116

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 See Also
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6rjh"

@@ Line 3: / Line 3: @@
 <SX load='6rjh' size='340' side='right' viewer='molstar' caption='[[6rjh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6rjh]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6rjh]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RJH FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjh OCA], [http://pdbe.org/6rjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rjh RCSB], [http://www.ebi.ac.uk/pdbsum/6rjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjh ProSAT]</span></td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjh OCA], [http://pdbe.org/6rjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rjh RCSB], [http://www.ebi.ac.uk/pdbsum/6rjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjh ProSAT]</span></td></tr>
 </table>
 == Function ==

6rjh

From Proteopedia

Revision as of 05:44, 11 April 2020

3D structure of horse spleen apoferritin determined using multifunctional graphene supports for electron cryomicroscopy

Structural highlights

Function

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox