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1aqr

From Proteopedia

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[[Image:1aqr.gif|left|200px]]
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{{STRUCTURE_1aqr| PDB=1aqr | SCENE= }}
{{STRUCTURE_1aqr| PDB=1aqr | SCENE= }}
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'''CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE'''
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===CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE===
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==Overview==
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3D solution structural calculations for yeast silver(I)-substituted metallothionein (MT) and native copper(I) MT were completed using experimentally determined NOE and dihedral angle constraints, in conjunction with experimentally derived metal-to-Cys connectivities for AgMT which were assumed identical for CuMT. For the first 40 residues in both structures, the polypeptide backbone wraps around the metal cluster in two large parallel loops separated by a deep cleft containing the metal cluster. Minor differences between the two structures include differences in hydrogen bonds and the orientation of the N-terminus with the overall protein volume conserved to within 6.5%.
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The line below this paragraph, {{ABSTRACT_PUBMED_8566237}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8566237 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8566237}}
==About this Structure==
==About this Structure==
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1AQR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQR OCA].
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1AQR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQR OCA].
==Reference==
==Reference==
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[[Category: Metal-thiolate cluster]]
[[Category: Metal-thiolate cluster]]
[[Category: Metallothionein]]
[[Category: Metallothionein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:35:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:25:45 2008''

Revision as of 14:25, 30 June 2008

Image:1aqr.png

Template:STRUCTURE 1aqr

CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE

Template:ABSTRACT PUBMED 8566237

About this Structure

1AQR is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

3D solution structure of copper and silver-substituted yeast metallothioneins., Peterson CW, Narula SS, Armitage IM, FEBS Lett. 1996 Jan 22;379(1):85-93. PMID:8566237

Page seeded by OCA on Mon Jun 30 17:25:45 2008

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