2ebt
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ebt' size='340' side='right'caption='[[2ebt]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2ebt' size='340' side='right'caption='[[2ebt]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2ebt]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ebt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. The April 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Oct and Sox Transcription Factors'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_4 10.2210/rcsb_pdb/mom_2009_4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBT FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebt OCA], [https://pdbe.org/2ebt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebt RCSB], [https://www.ebi.ac.uk/pdbsum/2ebt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebt ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebt TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/KLF5_HUMAN KLF5_HUMAN]] Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebt ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebt ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
- | |||
- | ==See Also== | ||
- | *[[Teaching Scenes%2C Tutorials%2C and Educators' Pages|Teaching Scenes%2C Tutorials%2C and Educators' Pages]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> |
Revision as of 17:22, 15 December 2021
Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5
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Categories: Human | Large Structures | Oct and Sox Transcription Factors | RCSB PDB Molecule of the Month | Hayashi, F | Nagashima, T | Structural genomic | Yokoyama, S | C2h2-type zinc-finger | Gc-box promoter element | Kruppel-like factor | Metal bind | National project on protein structural and functional analyse | Nppsfa | Rsgi | Transcription | Transcription factor