Tumor necrosis factor ligand superfamily
From Proteopedia
(Difference between revisions)
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== Function == | == Function == | ||
'''Tumor necrosis factor ligand superfamily''' (TNFLS) is a family of TNF-like ligands. These cytokines cause wide-ranging long-term cellular activities in cells such as differentiation, proliferation or death<ref>PMID:10891884</ref>, <ref>PMID:8905447</ref>. The TNFLS are ligands for the TNF receptors. | '''Tumor necrosis factor ligand superfamily''' (TNFLS) is a family of TNF-like ligands. These cytokines cause wide-ranging long-term cellular activities in cells such as differentiation, proliferation or death<ref>PMID:10891884</ref>, <ref>PMID:8905447</ref>. The TNFLS are ligands for the TNF receptors. | ||
| + | ==3D structures of tumor necrosis factor ligand superfamily== | ||
| + | [[Tumor necrosis factor ligand superfamily 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
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**[[3lkj]], [[1aly]] – hTNFLS5 - human <br /> | **[[3lkj]], [[1aly]] – hTNFLS5 - human <br /> | ||
| + | **[[6brb]] – hTNFLS5 + TN3-like<br /> | ||
* Tumor necrosis factor ligand superfamily member 6 | * Tumor necrosis factor ligand superfamily member 6 | ||
| - | **[[5l19]] – | + | **[[5l19]] – hTNFLS6 (mutant) <br /> |
| - | **[[5l36]], [[4msv]] – | + | **[[5l36]], [[4msv]] – hTNFLS6 + Dcr3 <br /> |
* Tumor necrosis factor ligand superfamily member 9 | * Tumor necrosis factor ligand superfamily member 9 | ||
| - | **[[6cpr]] – | + | **[[6cpr]] – hTNFLS9 + Tnf receptor superfanily member 9 <br /> |
| + | **[[6mge]], [[6d3n]] – hTNFLS 4-1BBL<br /> | ||
| + | **[[6mgp]], [[6fib]] – hTNFLS 4-1BB/4-1BBL<br /> | ||
| + | **[[6cu0]], [[6bwv]] – hTNFLS 4-1BB/4-1BBL (mutant)<br /> | ||
| + | **[[6mkb]] – mTNFLS 4-1BB - mouse <br /> | ||
| + | **[[6mkz]] – mTNFLS 4-1BB/4-1BBL <br /> | ||
* Tumor necrosis factor ligand superfamily member 10 see [[TRAIL]] | * Tumor necrosis factor ligand superfamily member 10 see [[TRAIL]] | ||
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**[[5bnq]] – hTNFLS11 + RANK <br /> | **[[5bnq]] – hTNFLS11 + RANK <br /> | ||
**[[3urf]] – hTNFLS11 + TNF receptor 11B <br /> | **[[3urf]] – hTNFLS11 + TNF receptor 11B <br /> | ||
| - | **[[1s55]], [[1jtz]] – mTNFLS11 | + | **[[1s55]], [[1jtz]] – mTNFLS11<br /> |
**[[4e4d]] – mTNFLS11 + TNF receptor 11B <br /> | **[[4e4d]] – mTNFLS11 + TNF receptor 11B <br /> | ||
**[[4giq]], [[3qbq]], [[3me2]] – mTNFLS11 + TNF receptor 11A<br /> | **[[4giq]], [[3qbq]], [[3me2]] – mTNFLS11 + TNF receptor 11A<br /> | ||
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**[[1xu2]] – mTNFLS13 + BCMA<br /> | **[[1xu2]] – mTNFLS13 + BCMA<br /> | ||
**[[3k48]] – mTNFLS13 extracellular domain + peptide<BR /> | **[[3k48]] – mTNFLS13 extracellular domain + peptide<BR /> | ||
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| + | * Tumor necrosis factor ligand superfamily member 13B (BAFF) | ||
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| + | **[[6fxn]] – hTNFLS13B + antibody <br /> | ||
* Tumor necrosis factor ligand superfamily member 14 | * Tumor necrosis factor ligand superfamily member 14 | ||
Revision as of 09:31, 15 March 2020
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3D structures of tumor necrosis factor ligand superfamily
Updated on 15-March-2020
References
- ↑ Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000 Aug 1;50(3):184-95. PMID:10891884 doi:<184::AID-JEMT2>3.0.CO;2-H http://dx.doi.org/10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H
- ↑ Gruss HJ. Molecular, structural, and biological characteristics of the tumor necrosis factor ligand superfamily. Int J Clin Lab Res. 1996;26(3):143-59. PMID:8905447
