Tyrosine phosphatase

== 3D Structures of tyrosine phosphatase ==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

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*'''Class I'''

*'''Non-receptor type tyrosine phosphatase'''

**[[5k9v]] – hPTPN1 - human<br />

**[[4qah]], [[4qap]], [[4qbe]], [[4qbw]], [[5kaa]], [[5ka8]], [[5ka4]], [[5ka2]], [[5ka1]], [[5ka0]] – hPTPN1 (mutant)<br />

**[[1a5y]], [[2hnp]], [[2hnq]], [[1oem]], [[1oeo]], [[1oes]], [[1oet]], [[1oeu]], [[1oev]], [[1sug]], [[2cm2]], [[2cm3]], [[3eu0]], [[3i80]], [[3a5j]], [[1bzc]], [[6b8e]], [[6b8t]], [[6b8x]], [[6b90]], [[6ntp]] - hPTP1B catalytic domain 1-321<br />

**[[1gfy]], [[1i57]], [[1pa1]], [[2f6f]], [[3a5k]], [[3zv2]], [[3qkp]], [[3qkq]], [[6bai]], [[6olq]], [[6olv]], [[6omy]], [[6pfw]], [[6pg0]], [[6pgt]], [[6pha]], [[6phs]], [[6cwv]], [[6cwu]] - hPTP1B catalytic domain (mutant) <br />

**[[3pdz]] - hPTP-1E PDZ2 domain – NMR<br />

**[[2b49]] – hPTPN3 catalytic domain<br />

**[[4qun]] – hPTPN3 catalytic domain (mutant) <br />

**[[2i75]] – hPTPN4<br />

**[[2cs5]] – hPTPN4 PDZ domain – NMR<BR />

**[[2vph]] - hPTPN4 PDZ domain<br />

**[[2bij]] – hPTPN5 catalytic domain<br />

**[[2bv5]] - hPTPN5 catalytic domain (mutant) <br />

**[[4hjp]], [[1gwz]], [[2b3o]] – hPTPN6 catalytic domain <br />

**[[4gry]], [[4grz]], [[4hjq]], [[3ps5]] – hPTPN6 catalytic domain (mutant)<br />

**[[2dn7]] - hPTPN6 FN3 #6 domain - NMR<br />

**[[2dju]], [[2edy]] - hPTPN6 FN3 domain - NMR<br />

**[[1x6c]] - hPTP hPTPN6 SH2 domain – NMR<BR />

**[[2a3k]], [[1zc0]] – hPTPN7 catalytic domain<br />

**[[2gp0]], [[2hvl]], [[2qdc]], [[2qdm]], [[2qdp]], [[2qds]], [[2qdt]], [[2qdu]], [[3o4s]], [[3o4t]], [[3o4u]] – hPTPN7 catalytic domain (mutant) <br />

**[[2pa5]] – hPTPN9 catalytic domain<br />

**[[3b7o]], [[3zm0]], [[3zm1]], [[3zm2]], [[3zm3]] - hPTPN11 catalytic domain<br />

**[[4dgp]] - hPTPN11 SH2+catalytic domains<br />

**[[4dgx]], [[4gwf]], [[4h1o]], [[4h34]], [[4nwf]], [[4nwg]], [[4ohd]], [[4ohe]], [[4ohh]], [[4ohi]], [[4ohl]] - hPTPN11 SH2+catalytic domains (mutant)<br />

**[[5j8r]], [[5i6v]], [[5ibm]], [[5ibs]], [[6atd]], [[2shp]] - hPTPN11 catalytic domain (mutant)<br />

**[[5hde]] - hPTPN12 catalytic domain <br />

**[[5glj]] - hPTPN13 PDZ1 domain <br />

**[[3lnx]] – hPTPN13 PDZ2 domain<br />

**[[3pdz]] - hPTPN13 PDZ2 domain – NMR<BR />

**[[2m0z]] - hPTPN13 PDZ2 domain (mutant) – NMR<br />

**[[2bzl]] – hPTPN14 catalytic domain<br />

**[[2oc3]] – hPTPN18<br />

**[[2p6x]], [[2qcj]], [[3h2x]] – hPTPN22 catalytic domain<br />

**[[5cru]], [[5mjz]], [[3rau]] – hRPTP23 domain Bro residues 1-361<br />

**[[5lm2]] – hRPTP23 residues 362-713<br />

**[[1xm2]], [[1rxd]] – hPTP PRL-1<br />

**[[1r6h]], [[1v3a]], [[2mbc]] – hPTP PRL-3 – NMR<BR />

**[[1rxd]] - hPTP IVA-1<br />

**[[1gwz]], [[2b3o]] – hPTP SHP-1 catalytic domain<br />

**[[1x6c]] - hPTP SHP-1 SH2 domain 105-220 – NMR<br />

**[[6cmq]] - hPTP SHP-2 106-529<br />

2shp, [[6ihz]], [[6crf]], [[6cmp]] - hPTP SHP-2 (mutant)**[[1c0e]] – bPTP (mutant) – bovine<br />

**[[1gm1]] - mPTP-BL PDZ2 domain – mouse – NMR<BR />

**[[1ozi]] - mPTP-BL PDZ2 domain (mutant) – NMR<BR />

**[[3rgo]] – mPTP-1<br />

**[[2yz1]] – mPTP SHPS-1 catalytic domain<br />

**[[1zck]], [[1x24]] – rPTP 4A1 – rat<br />

**[[3i36]] – rPTP-η catalytic domain<br />

**[[2pi7]] – cPTP CRYP-2 catalytic domain - chicken<br />

**[[1d1p]], [[2j16]], [[6byf]] – yPTP - yeast<br />

**[[2j17]] - yPTP (mutant)<br />

**[[5xw4]] – yPTPN CDC14 <br />

**[[1g4w]] – StPTP – ''Salmonella typhimurium''<br />

**[[2i6i]], [[3ro1]] – SsPTP – ''Sulfolobus solfataricus''<br />

**[[2z72]], [[1v73]], [[2zbm]] – PTP residues 22-361 – ''Shewanella''<br />

**[[3js5]], [[3jvi]] – EhPTP – ''Entamoeba histolytica''<br />

**[[2wjd]], [[2wje]], [[2wjf]] – PTP – ''Streptococcus pneumonia''<br />

**[[5z59]], [[5z5a]] – TkPTP – ''Thermococcus kodakarensis'' <br />

**[[5z5b]] - TkPTP (mutant)<br />

**[[3qy6]], [[3qy7]], [[3qy8]] – BsPTP – ''Bacillus subtilis''

*Non-receptor type PTP complex with peptide

**[[3zmp]], [[3zmq]], [[4zrt]] – hPTPN1 catalytic domain + peptide<br />

**[[3i7z]] - hPTP1B catalytic domain + peptide<br />

**[[1ptt]], [[1ptu]], [[1g1f]], [[1g1g]], [[1g1h]], [[1een]], [[1eeo ]] - hPTP1B catalytic domain (mutant) + peptide<br />

**[[1bzh]] - hPTP1B catalytic domain + fluoromalonyl tyrosine peptide<br />

**[[1bzj]] - hPTP1B catalytic domain + phosphotyrosine mimetic<br />

**[[6hks]] – hPTPN3 489-597 + peptide<br />

**[[4qum]], [[4rh5]], [[4rh9]], [[4rhg]], [[4s0g]] – hPTPN3 catalytic domain (mutant) 628-909 + peptide<br />

**[[3nfk]], [[3nfl]], [[5eyz]], [[5ez0]] - hPTPN4 PDZ domain + peptide<br />

**[[2yu7]], [[2rmx]] – hPTPN6 SH2 domain + peptide – NMR<BR />

**[[4gs0]], [[1fpr]] – hPTPN6 catalytic domain + peptide<br />

**[[3d42]], [[3d44]] – hPTPN7 catalytic domain (mutant) + peptide<br />

**[[4icz]] – hPTPN9 catalytic domain + peptide<br />

**[[3tl0]], [[3tkz]],[[5df6]], [[4qsy]],[[5x94]], [[5x7b]] – hPTPN11 SH2 domain + peptide<br />

**[[5o2p]] – hPTPN12 SH3 domain/peptide<br />

**[[3lny]] - hPTPN13 PDZ2 domain + peptide<br />

**[[4gfu]], [[4gfv]] - hPTPN18 residues 6-300 + peptide<br />

**[[4nnd]] - hPTPN18 residues 6-300 (mutant) + ERBB-2<br />

**[[3brh]], [[3olr]] - hPTPN22 catalytic domain + peptide<br />

**[[3omh]] - hPTPN22 catalytic domain (mutant) + peptide<br />

**[[5crv]], [[5mk3]], [[5mk2]], [[5mk1]], [[5mk0]], [[5mjy]] – hRPTP23 domain Bro + STAM2 peptide<br />

**[[5lm1]] – hRPTP23 residues 362-713 + UBAP-1 peptide<br />

**[[1fpr]] - hPTP SHP-1 catalytic domain + peptide<br />

**[[6roy]] - hPTP SHP-2 N- terminal SH2 domain 1-104 + ITIM peptide <br />

**[[6roz]] - hPTP SHP-2 N- terminal SH2 domain 1-104 + ITSM peptide <br />

**[[6r5g]] - hPTP SHP-2 SH2 domain 105-220 + ITSM peptide – NMR<br />

**[[3rz2]] - rPTP 4A1 + peptide<br />

**[[1aya]], [[1ayb]], [[1ayc]], [[1ayd]] – mPTP Syp N terminal SH2 domain + peptide<br />

**[[1vj6]] – mPTP-BL PDZ2 domain + APC C terminal – NMR<br />

**[[6gbe]] – mPTPN13 PDZ3 domain + PRK2 peptide – NMR<br />

**[[5xw5]] – yPTPN CDC14 + SWI6 peptide<br />

**[[6g86]] – yPTPN CDC14 + SIC1 peptide<br />

**[[6g85]], [[6g84]] – yPTPN CDC14 + CBK1 peptide<br />

**[[2dxp]], [[2i6o]] – SsPTP (mutant) + peptide<br />

*Non-receptor type PTP complex with small molecule

**[[1ptv]], [[1pty]] - hPTP1B catalytic domain (mutant) + phosphotyrosine<br />

**[[1aax]] - hPTP1B catalytic domain (mutant) + bis-phosphophenyl methane<br />

**[[1ecv]], [[1c83]], [[1c84]], [[1c85]], [[1c86]], [[1c87]], [[1c88]], [[1g7f]], [[1g7g]], [[1jf7]], [[1l8g]], [[1kak]], [[1kav]], [[1lqf]], [[1nl9]], [[1nny]], [[1no6]], [[1nz7]], [[1ony]], [[1onz]], [[1ph0]], [[1pxh]], [[1pyn]], [[1q1m]], [[1q6j]], [[1q6m]], [[1q6n]], [[1q6p]], [[1q6s]], [[1q6t]], [[1qxk]], [[1t48]], [[1t49]], [[1t4j]], [[1xbo]], [[1wax]], [[2bgd]], [[2bge]], [[2azr]], [[2b07]], [[2f6t]], [[2f6v]], [[2f6w]], [[2f6y]], [[2f6z]], [[2f70]], [[2f71]], [[2fjn]], [[2cm7]], [[2cm8]], [[2cma]], [[2cmb]], [[2cmc]], [[2h4g]], [[2h4k]], [[2hb1]], [[2cne]], [[2cnf]], [[2cng]], [[2cnh]], [[2cni]], [[2nt7]], [[2nta]], [[2veu]], [[2vev]], [[2vew]], [[2vex]], [[2vey]], [[2qbp]], [[2qbq]], [[2qbr]], [[2qbs]], [[3cwe]], [[3d9c]], [[2zmm]], [[2zn7]], [[3eax]], [[3eb1]], [[3sme]], [[4i8n]], [[4y14]], [[6bmr]], [[6bmv]], [[6bmx]], [[6bmu]], [[6bmw]], [[6bmy]], [[5t19]], [[5k9w]], [[6b8z]], [[5t19]], [[5k9w]] - hPTP1B catalytic domain + inhibitor<br />

**[[5kad]], [[5kac]], [[5kab]], [[5ka9]], [[5ka7]], [[5ka3]], [[6b95]], [[1nwl]], [[1nwe]], [[2fjm]], [[6bn5]], [[5kad]], [[5kac]], [[5kab]], [[5ka9]], [[5ka7]], [[5ka3]], [[5qgf]], [[5qge]], [[5qgd]], [[5qgc]], [[5qgb]], [[5qga]], [[5qg9]], [[5qg8]], [[5qg7]], [[5qg6]], [[5qg5]], [[5qg4]], [[5qg3]], [[5qg2]], [[5qg1]], [[5qg0]], [[5qfz]], [[5qfx]], [[5qfw]], [[5qfv]], [[5qfu]], [[5qft]], [[5qfs]], [[5qfr]], [[5qfq]], [[5qfp]], [[5qfo]], [[5qfn]], [[5qfm]], [[5qfl]], [[5qfk]], [[5qfj]], [[5qfi]], [[5qfh]], [[5qfg]], [[5qff]], [[5qfe]], [[5qfd]], [[5qfc]], [[5qfb]], [[5qfa]], [[5qf9]], [[5qf8]], [[5qf7]], [[5qf6]], [[5qf5]], [[5qf4]], [[5qf3]], [[5qf2]], [[5qf1]], [[5qf0]], [[5qez]], [[5qex]], [[5qew]], [[5qev]], [[5qeu]], [[5qet]], [[5qes]], [[5qer]], [[5qeq]], [[5qep]], [[5qeo]], [[5qen]], [[5qem]], [[5qel]], [[5qek]], [[5qej]], [[5qei]], [[5qeh]], [[5qeg]], [[5qef]], [[5qee]], [[5qed]], [[5qec]], [[5qeb]], [[5qea]], [[5qe9]], [[5qe8]], [[5qe7]], [[5qe6]], [[5qe5]], [[5qe4]], [[5qe3]], [[5qe2]], [[5qe1]], [[5qe0]], [[5qdz]], [[5qdx]], [[5qdw]], [[5qdv]], [[5qdu]], [[5qdt]], [[5qds]], [[5qdr]], [[5qdq]], [[5qdp]], [[5qdo]], [[5qdn]], [[5qdm]], [[5qdl]], [[5qdk]], [[5qdj]], [[5qdi]], [[5qdh]], [[5qdg]], [[5qdf]] - hPTPN1B (mutant) + inhibitor<br />

**[[4bjo]] – hPTP1 catalytic domain + NO3<br />

**[[6pm8]] – hPTPN1b (mutant) + VO4<br />

**[[4ri4]], [[4ri5]] – hPTPN3 catalytic domain (mutant) + VO4<br />

**[[6h8r]] – hPTPN5 + inhibitor<br />

**[[2cjz]] - hPTPN5 catalytic domain (mutant) 258-563 + phosphotyrosine<br />

**[[5ow1]], [[5ovx]], [[5ovr]] – hPTP5 catalytic domain + inhibitor<br />

**[[4ge2]], [[4ge5]], [[4ge6]] – hPTP9 catalytic domain + inhibitor<br />

**[[3o5x]], [[4pvg]], [[5ehp]], [[5ehr]], [[4rdd]] – hPTPN11 catalytic domain + inhibitor<br />

**[[3mow]] - hPTPN11 catalytic domain + tautomycetin analog<br />

**[[2m10]] - hPTPN13 PDZ2 domain (mutant) + azobenzene derivative – NMR<br />

**[[2qct]], [[4j51]] – hPTPN22 catalytic domain + inhibitor<br />

**[[5h08]] – hPTP ζ D1 domain + inhibitor<br />

**[[5bx1]] – hPTP PRL-1 + inhibitor<br />

**[[6md7]], [[6md9]], [[6mda]], [[6mdb]], [[6mdc]], [[6mdd]], [[5xzr]] - hPTP SHP-2 + inhibitor<br />

**[[6crg]], [[6cms]], [[6cmr]] - hPTP SHP-2 (mutant) + inhibitor<br />

**[[1dg9]] – bPTP + HEPES<br />

**[[1zcl]] - rPTP 4A1 (mutant) + sulfate<br />

**[[1d2a]] – yPTP + adenine <br />

**[[1d1q]] – yPTP (mutant) + PNPP<br />

**[[2i6p]] - SsPTP (mutant) + PNPP<br />

**[[2i6j]] – SsPTP + phosphate<br />

**[[2i6m]] – SsPTP + WO4<BR />

**[[3ido]] – EhPTP + HEPES<br />

**[[3rgq]] – mPTP-1 + Pi(5)P<br />

**[[6h8s]] – mPTPN5 + inhibitor<br />

*Non-receptor type PTP complex with protein

**[[2b4s]] - hPTP1B catalytic domain + insulin receptor<br />

**[[2gph]] - hPTPN7 catalytic domain (mutant) + MAPK2<br />

**[[4je4]], [[4jeg]] – hPTPN11 catalytic domain + monobody<br />

**[[6iwd]] – hPTPN14 886-1187 + HPV18 CR3 domain<br />

**[[5k25]], [[5k24]], [[5k23]] – hPTP PRL-2 + CNNM3<br />

**[[5k22]] – hPTP PRL-2 (mutant) + CNNM3<br />

**[[5tsr]] – hPTP PRL-3 (mutant) + CNNM3<br />

**[[6nmv]], [[6nmu]], [[6nmt]], [[6nms]], [[6nmr]], [[6bit]] - hPTP SHPS-1 + antibody<br />

**[[5lxq]] – mPTP + CNNM2<br />

**[[5mmz]] – mPTP 4A1 + CNNM2<br />

**[[4zj7]] – yPTPN CDC14 C terminal + importin<br />

**[[1g4u]] – StPTP + RAS-related C3 botulinum toxin substrate <br />

**[[1jyo]] – StPTP + secretion chaperone SICP<br />

*'''Yersinia tyrosine phosphatase Yop'''

**[[1yts]], [[4yaa]], [[4z6b]], [[4zi4]], [[4zn5]] - YePTP catalytic domain (mutant) – ''Yersinia enterocolitica''<br />

**[[1xxp]], [[1xxv]] - YePTP catalytic domain (mutant) + peptide<br />

**[[2i42]] – YePTP (mutant) + VO4<br />

**[[1ypt]], [[1ytw]] – YePTP catalytic domain + WO4<br />

**[[1ytn]] - YePTP catalytic domain + NO3<br />

**[[1lyv]] - YePTP catalytic domain (mutant) + phosphate<br />

**[[1pa9]], [[3bm8]] - YePTP catalytic domain (mutant) + inhibitor<br />

**[[3u96]] - YePTP catalytic domain (mutant) + PNCS<br />

**[[1huf]] – YpPTP - ''Yersinia pestis''<br />

**[[1qz0]] - YpPTP catalytic domain + peptide<br />

**[[2y2f]] - YpPTP catalytic domain + inhibitor<br />

**[[1k46]] - YpPTP N terminal domain<br />

**[[1m0v]] - YpPTP N terminal domain + peptide – NMR<br />

**[[4gf3]] – YpPTP + Yop targeting protein<br />

*'''Receptor-type tyrosine phosphatase'''

**[[1yfo]], [[2i1y]] – mRPTP-α catalytic domain<br />

**[[1p15]] - mRPTP-α D2 domain<br />

**[[3pxh]] - mRPTP Ig domains<br />

**[[1jln]], [[2a8b]] - mRPTP-R catalytic domain<br />

**[[3sr9]] - mRPTP-σ residues 1326 – 1901<br />

**[[2nv5]] – rRPRP<br />

**[[2yd4]] - cRPTP-σ Ig1-2 domain – chicken<br />

**[[2yd1]], [[2yd2]], [[3pxj]] – DmRPTP Ig1-2 domain – ''Drosophila melanogaster''<br />

**[[3s3e]] – DmRPTP-10D catalytic domain<br />

*'''Human receptor-type tyrosine phosphatase'''

**[[2ahs]] – hRPTP-β<br />

**[[2i3r]], [[2i5x]] - hRPTP-β catalytic domain<br />

**[[2hc1]], [[2hc2]] - hRPTP-β catalytic domain (mutant) <br />

**[[2h4v]], [[2pbn]], [[3qcb]] – hRPTP-γ domain 1<br />

**[[3qcn]] - hRPTP-γ domain 1 (mutant) <br />

**[[2nlk]] - hRPTP-γ catalytic domain<br />

**[[3jxh]] - hRPTP-γ CA-like domain<br />

**[[5fmv]] - hRPTP-γ domain D1-D4<br />

**[[5fn6]] - hRPTP-γ domain D1-D3<br />

**[[5fn7]] - hRPTP-γ domain D1-D2<br />

**[[5fn8]] - rRPTP-γ domain D3-D4<br />

**[[4yfe]] - hRPTP-δ FN1-FN2 domain 321-511<br />

**[[4yfg]] - hRPTP-δ Ig1-FN1 domain 21-501<br />

**[[2dlh]], [[1x5z]] - hRPTP-δ FN3 domain 405-514 – NMR<BR />

**[[2yd6]], [[2yd7]] - hRPTP-δ Ig1-2 domain 21-220<br />

**[[2jjd]] - hRPTP-ε residues 107-697<br />

**[[6d4d]] - hRPTP-ε domain D1 residues 22-313<br />

**[[6d4f]], [[6d3f]] - hRPTP-ε domain D2 residues 425-700<br />

**[[2c7s]] - hRPTP-κ residues 865-1154<br />

**[[2c7s]] - hRPTP-κ residues 865-1154<br />

**[[1rpm]] - hRPTP-μ catalytic domain<br />

**[[2c9a]] - hRPTP-μ MAM-IG module<br />

**[[2v5y]] - hRPTP-μ extracellular region<br />

**[[2g59]], [[2gjt]] - hRPTP-ο catalytic domain<br />

**[[2cfv]] – hRPTP-η residues 1019-1311<br />

**[[2nz6]] - hRPTP-η residues 1019-1311 (mutant) <br />

**[[2dle]] - hRPTP-η FN3 domain – NMR<BR />

**[[2qep]] – hRPTP-ν2 D1 domain<br />

**[[4hti]], [[4htj]] – hRPTP-ν2 membrane proximal ectodomain<br />

**[[2ooq]] – hRPTP-ρ<br />

**[[2fh7]], [[4bpc]] - hRPTP-σ catalytic domain (mutant) <br />

**[[2yd9]] - hRPTP-σ Ig1-3 domain (mutant) <br />

**[[2yd3]], [[2yd5]] - hRPTP-σ Ig1-2 domain<br />

**[[4pbx]] - hRPTP-σ residues 30-588<br />

**[[3jxf]] - hRPTP-ζ CA-like domain<br />

**[[5awx]] - hRPTP-ζ D1 domain<br />

**[[2qt7]], [[3n01]], [[3n4w]], [[3ng8]], [[3np5]] – hRPTP IA-2<br />

**[[4n5u]] - hRPTP-F FN3 domain<br />

**[[2edx]] - hRPTP-F FN3 domain – NMR<BR />

**[[6j6u]] - rRPTP-ζ D1-D2 domain<br />

**[[3jxg]], [[3jxh]] - mRPTP-γ CA-like domain<br />

*Receptor type tyrosine phosphatase complexes

**[[2h02]], [[2h04]], [[2i3u]], [[2i4e]], [[2i4g]], [[2i4h]] - hRPTP-β catalytic domain + inhibitor<br />

**[[2h03]] - hRPTP-β catalytic domain (mutant) + inhibitor<br />

**[[2hy3]], [[3qcc]], [[3qcd]] - hRPTP-γ domain 1 + VO4<BR />

**[[3qce]], [[3qcf]], [[3qcg]], [[3qch]], [[3qci]], [[3qcj]], [[3qck]] - hRPTP-γ domain 1 + inhibitor<br />

**[[3qcl]], [[3qcm]] - hRPTP-γ domain 1 (mutant) + inhibitor<br />

**[[5e5r]] - hRPTP-γ domain CA + contactin 3<br />

**[[4rca]], [[4y61]] - hRPTP-δ Ig1-Ig2 domain 21-318 + SLITRK1<br />

**[[5xnp]] - hRPTP-δ Ig1-Ig2 domain (mutant) + SALM5<br />

**[[6kip]] - hRPTP-δ residues 1617-1912 + liprin<br />

**[[5y32]], [[4yfd]], [[4yh7]], [[5wy8]] - hRPTP-δ Ig1-Ig2 domain + IL1RAPL1<br />

**[[5xnp]] - hRPTP-d Ig1-Ig2 domain (mutant) + SALM5<br />

**[[6kip]] - hRPTP-d residues 1617-1912 + liprin<br />

**[[2yd8]] - hRPTP-σ Ig1-2 domain + sucrose octasulfate<br />

**[[3s97]] - hRPTP-ζ CA-like domain + congtactin Ig domains<br />

**[[5h08]] – hPTP ζ D1 domain 1698-1993 + inhibitor<br />

**[[6kr4]] - hRPTP-F residues 1332-1907 + liprin<br />

**[[1ygr]] – hRPTP CD45 cytoplasmic domain (mutant) + T-cell receptor peptide<br />

**[[5e5u]] - mRPTP-γ domain CA + contactin 6<br />

**[[3kld]] - mRPTP-γ CA-like domain + contactin 4<br />

**[[5xwu]] - mRPTP- Ig1-Ig3 domain + LRR-IG<br />

**[[5xwt]] - mRPTP- Ig1-FN1 domain + LRR-IG<br />

**[[3s3f]] - DmRPTP-10D catalytic domain + VO4<BR />

**[[3s3h]] - DmRPTP-10D catalytic domain + peptide<br />

**[[3s3k]] - DmRPTP-10D catalytic domain + inhibitor<br />

*'''Dual-specificity tyrosine phosphatase or Dual-specificity protein phosphatase''' See [[MAP kinase phosphatase]].

*'''Class II'''

*'''Low molecular weight tyrosine phosphatase (LMW-PTP)'''

**[[1xww]], [[4z99]], [[5pnt]] - hLMW-PTP <br />

**[[1phr]] - bLMW-PTP<br />

**[[1p8a]] – LMW-PTP (mutant) – ''Tritrichomonas foetus'' – NMR<BR />

**[[2cwd]] – LMW-PTP – ''Thermus thermophilus''<br />

**[[5got]] – LMW-PTP – ''Streptococcus pyogenes''<br />

**[[5z3m]] – LMW-PTP – ''Vibrio cholerae''<br />

**[[1u2p]], [[2luo]] – MtLMW-PTP – ''Mycobacterium tuberculosis''<br />

**[[2oz5]] – MtLMW-PTP + inhibitor<br />

**[[2fek]] – LMW-PTP – ''Escherichia coli''<br />

**[[4eti]], [[4etm]], [[4kk3]] – BsLMW-PTP<br />

**[[4etn]], [[4kk4]] – BsLMW-PTP (mutant)<br />

*LMW-PTP complex

**[[5kqg]], [[5kql]], [[5kqm]], [[5kqp]] – hLMW-PTP + inhibitor<br />

**[[4z9a]] – hLMW-PTP + phenylmethanesulfonic acid<br />

**[[4z9b]] – hLMW-PTP + benzylphosphonic acid<br />

**[[1z12]] - bLMW-PTP + VO4<br />

**[[1z13]] - bPTP + MoO4<br />

**[[5jnw]] – bLMW-PTP + inhibitor <br />

**[[3rof]] – LMW-PTP-A + peptide – ''Staphylococcus aureus''<br />

**[[1u2q]] – MtLMW-PTP + glycerol<br />

**[[2oz5]] – MtLMW-PTP + inhibitor<br />

*'''Class III or M-phase inducer phosphatase 2'''

*'''CDC25'''

**[[1c25]] – hCDC25A catalytic domain (mutant) <br />

**[[1qb0]], [[1cwr]], [[1ym9]], [[1ymd]], [[1ymk]], [[1yml]], [[1ys0]], [[2uzq]] - hCDC25B catalytic domain<br />

**[[2a2k]], [[2ifd]], [[2ifv]] - hCDC25B catalytic domain (mutant) <br />

**[[4wh7]] - hCDC25B catalytic domain (mutant) + ligand<br />

**[[4wh9]] - hCDC25B catalytic domain (mutant) + inhibitor<br />

**[[1cwr]], [[1cws]] - hCDC25B catalytic domain + WO4<BR />

**[[1cwt]] - hCDC25B catalytic domain + Methyl-Hg<br />

**[[3op3]] – hCDC25C residues 270-462

*'''Class IV'''

**[[4tvv]] – PTP – ''Legionella pneumophila''<br />

*'''T-cell tyrosine phosphatase'''

**[[1l8k]] – hTC-PTP

*'''Other tyrosine phosphatases'''

**[[4az1]] – PTP – ''Trypanosoma cruzi''<br />

**[[4r0s]] – PaPTP – ''Pseudomonas aeruginosa''<br />

**[[4r0t]] – PaPTP (mutant) + tyrosine<br />

**[[5ncr]] – PTP (mutant) – ORF virus<br />

}}