2eqo
From Proteopedia
(Difference between revisions)
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<StructureSection load='2eqo' size='340' side='right'caption='[[2eqo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2eqo' size='340' side='right'caption='[[2eqo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2eqo]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2eqo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQO FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqo OCA], [https://pdbe.org/2eqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqo RCSB], [https://www.ebi.ac.uk/pdbsum/2eqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqo ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqo TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MIPT3_HUMAN MIPT3_HUMAN]] Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.<ref>PMID:10791955</ref> <ref>PMID:12935900</ref> <ref>PMID:12812986</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 15:56, 22 December 2021
Solution structure of the stn_TRAF3IP1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [Homo sapiens]
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