Sandbox Reserved 1606
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
===Overall 3D Structure=== | ===Overall 3D Structure=== | ||
- | + | [[Image:membrane domains.png|200 px|right|thumb|FIGURE LEGEND]] NBD - binding site for atp Homodimer | |
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===ATP Bound and Unbound Conformations=== | ===ATP Bound and Unbound Conformations=== | ||
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===Cavities and Lysine Plug=== | ===Cavities and Lysine Plug=== | ||
+ | [[Image:Cavity 1.png|200 px|left|thumb|FIGURE LEGEND]] | ||
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Revision as of 13:05, 24 March 2020
This Sandbox is Reserved from Jan 13 through September 1, 2020 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1598 through Sandbox Reserved 1627. |
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ABCG2 Multidrug Transporter
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References
- ↑ 1.0 1.1 1.2 Taylor NMI, Manolaridis I, Jackson SM, Kowal J, Stahlberg H, Locher KP. Structure of the human multidrug transporter ABCG2. Nature. 2017 Jun 22;546(7659):504-509. doi: 10.1038/nature22345. Epub 2017 May, 29. PMID:28554189 doi:http://dx.doi.org/10.1038/nature22345
- ↑ 2.0 2.1 Manolaridis I, Jackson SM, Taylor NMI, Kowal J, Stahlberg H, Locher KP. Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. Nature. 2018 Nov;563(7731):426-430. doi: 10.1038/s41586-018-0680-3. Epub 2018 Nov, 7. PMID:30405239 doi:http://dx.doi.org/10.1038/s41586-018-0680-3