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= Bd oxidase in ''E. coli'' = | = Bd oxidase in ''E. coli'' = | ||
<StructureSection load='6rx4' size='350' frame='true' side='right' caption='Bd oxidase' scene='83/832931/Full/2'>TextToBeDisplayed</scene’> | <StructureSection load='6rx4' size='350' frame='true' side='right' caption='Bd oxidase' scene='83/832931/Full/2'>TextToBeDisplayed</scene’> | ||
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<scene name='83/832931/Full/2'>TextToBeDisplayed</scene> | <scene name='83/832931/Full/2'>TextToBeDisplayed</scene> | ||
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
=== H and O channels === | === H and O channels === | ||
| + | The hydrogen and oxygen channels are essential for hydrogen and oxygen molecules to reach the active site of bd oxidase. Protons from the cytoplasm flow through a water-filled hydrophilic channel entering at D119<sup>A</sup> and moving past K57<sup>A</sup>, K109<sup>B</sup>, D105<sup>B</sup>, Y379<sup>B</sup>, and D58<sup>B</sup> <ref name="Theßeling">PMID:31723136</ref> where they can be transferred to the active site. | ||
=== Hemes === | === Hemes === | ||
== Applications == | == Applications == | ||
Revision as of 23:40, 23 March 2020
| This Sandbox is Reserved from Jan 13 through September 1, 2020 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1598 through Sandbox Reserved 1627. |
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Bd oxidase in E. coli
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References
- ↑ Thesseling A, Rasmussen T, Burschel S, Wohlwend D, Kagi J, Muller R, Bottcher B, Friedrich T. Homologous bd oxidases share the same architecture but differ in mechanism. Nat Commun. 2019 Nov 13;10(1):5138. doi: 10.1038/s41467-019-13122-4. PMID:31723136 doi:http://dx.doi.org/10.1038/s41467-019-13122-4
Student Contributors
- Grace Bassler
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