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Vinculin

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*Vinculin; Domains - Vd1 140-327; tail 878-1066
+
*Vinculin; Domains - head 140-327; tail 878-1066
**[[1tr2]], [[6fuy]] – hVCL - human<br />
**[[1tr2]], [[6fuy]] – hVCL - human<br />
 +
**[[3h2u]] – hVCL head domain + raver1 RRM <br />
 +
**[[2ibf]], [[2hsq]], [[2gww]] - hVCL head domain + SfVCL binding sites from ''Shigella flexneri''<br />
 +
**[[1ydi]] - hVCL head domain +hActinin VBS<br />
 +
**[[1syq]], [[1rkc]], [[1rke]] – hVCL head domain +hTalin VBS<br />
**[[1qkr]] – hVCL tail domain<br />
**[[1qkr]] – hVCL tail domain<br />
**[[3h2v]] - hVCL tail domain + raver1 RRM<br />
**[[3h2v]] - hVCL tail domain + raver1 RRM<br />
**[[4pr9]] - hVCL tail domain + lipid<br />
**[[4pr9]] - hVCL tail domain + lipid<br />
**[[3jbi]] - hVCL tail domain + actin – Cryo-EM<br />
**[[3jbi]] - hVCL tail domain + actin – Cryo-EM<br />
-
**[[3h2u]] – hVCL Vd1 + raver1 RRM <br />
 
-
**[[2ibf]], [[2hsq]], [[2gww]] - hVCL Vd1 + SfVCL binding sites from ''Shigella flexneri''<br />
 
-
**[[1ydi]] - hVCL Vd1+hActinin VBS<br />
 
-
**[[1syq]], [[1rkc]], [[1rke]] – hVCL Vd1+hTalin VBS<br />
 
**[[6nr7]] - cVCL – chicken<br />
**[[6nr7]] - cVCL – chicken<br />
-
**[[1t01]] - cVCL Vd1+mTalin VBS<br />
+
**[[1t01]] - cVCL head domain +mTalin VBS<br />
-
**[[3zdl]] – cVCL Vd1 + amyloid β precursor protein N terminal<br />
+
**[[3zdl]] – cVCL head domain + amyloid β precursor protein N terminal<br />
*Metavinculin; Domains - head 1-256; tail 959-1134
*Metavinculin; Domains - head 1-256; tail 959-1134

Revision as of 10:54, 25 March 2020

Chicken full-length metavinculin, 1st6

Drag the structure with the mouse to rotate

3D Structures of Vinculin

Updated on 25-March-2020

References

  1. Palovuori R, Eskelinen S. Role of vinculin in the maintenance of cell-cell contacts in kidney epithelial MDBK cells. Eur J Cell Biol. 2000 Dec;79(12):961-74. PMID:11152287 doi:http://dx.doi.org/10.1078/0171-9335-00120
  2. Li T, Guo H, Song Y, Zhao X, Shi Y, Lu Y, Hu S, Nie Y, Fan D, Wu K. Loss of vinculin and membrane-bound beta-catenin promotes metastasis and predicts poor prognosis in colorectal cancer. Mol Cancer. 2014 Dec 11;13:263. doi: 10.1186/1476-4598-13-263. PMID:25496021 doi:http://dx.doi.org/10.1186/1476-4598-13-263
  3. Vasile VC, Will ML, Ommen SR, Edwards WD, Olson TM, Ackerman MJ. Identification of a metavinculin missense mutation, R975W, associated with both hypertrophic and dilated cardiomyopathy. Mol Genet Metab. 2006 Feb;87(2):169-74. Epub 2005 Oct 19. PMID:16236538 doi:S1096-7192(05)00258-1

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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