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6sbi

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Current revision (12:38, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6sbi' size='340' side='right'caption='[[6sbi]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='6sbi' size='340' side='right'caption='[[6sbi]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6sbi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SBI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6sbi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SBI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbi OCA], [http://pdbe.org/6sbi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sbi RCSB], [http://www.ebi.ac.uk/pdbsum/6sbi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbi ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbi OCA], [https://pdbe.org/6sbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sbi RCSB], [https://www.ebi.ac.uk/pdbsum/6sbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FAHD1_MOUSE FAHD1_MOUSE]] Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro (By similarity). Also has oxaloacetate decarboxylase activity (PubMed:25575590).[UniProtKB:Q6P587]<ref>PMID:25575590</ref>
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[https://www.uniprot.org/uniprot/FAHD1_MOUSE FAHD1_MOUSE] Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro (By similarity). Also has oxaloacetate decarboxylase activity (PubMed:25575590).[UniProtKB:Q6P587]<ref>PMID:25575590</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Naschberger, A]]
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[[Category: Mus musculus]]
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[[Category: Rupp, B]]
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[[Category: Naschberger A]]
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[[Category: Weiss, A K.H]]
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[[Category: Rupp B]]
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[[Category: Hydrolase]]
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[[Category: Weiss AKH]]
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[[Category: Mitochondria]]
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[[Category: Oxalate binding]]
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[[Category: Tca cycle]]
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Current revision

X-ray structure of murine Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in complex with inhibitor oxalate

PDB ID 6sbi

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