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5chp

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<StructureSection load='5chp' size='340' side='right'caption='[[5chp]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5chp' size='340' side='right'caption='[[5chp]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5chp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5chp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CHP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=51Q:(2S)-2-[(3-HYDROXY-5-OXO-4,5-DIHYDRO-1,2,4-TRIAZIN-6-YL)SULFANYL]PROPANOIC+ACID'>51Q</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=51Q:(2S)-2-[(3-HYDROXY-5-OXO-4,5-DIHYDRO-1,2,4-TRIAZIN-6-YL)SULFANYL]PROPANOIC+ACID'>51Q</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">thyX, thy1, TM_0449 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5chp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chp OCA], [https://pdbe.org/5chp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5chp RCSB], [https://www.ebi.ac.uk/pdbsum/5chp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5chp ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase_(FAD) Thymidylate synthase (FAD)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.148 2.1.1.148] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5chp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chp OCA], [http://pdbe.org/5chp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5chp RCSB], [http://www.ebi.ac.uk/pdbsum/5chp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5chp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.
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[https://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43589]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Abell, C A]]
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[[Category: Thermotoga maritima]]
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[[Category: Blundell, T L]]
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[[Category: Abell CA]]
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[[Category: Costi, M P]]
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[[Category: Blundell TL]]
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[[Category: Ferrari, S]]
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[[Category: Costi MP]]
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[[Category: Luciani, R]]
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[[Category: Ferrari S]]
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[[Category: Marverti, G]]
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[[Category: Luciani R]]
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[[Category: Ponterini, G]]
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[[Category: Marverti G]]
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[[Category: Santucci, M]]
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[[Category: Ponterini G]]
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[[Category: Saxena, P]]
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[[Category: Santucci M]]
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[[Category: Surade, S]]
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[[Category: Saxena P]]
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[[Category: Venturelli, A]]
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[[Category: Surade S]]
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[[Category: Hydrolase]]
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[[Category: Venturelli A]]
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[[Category: Thyx in complex with inhibitor]]
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Revision as of 12:06, 14 June 2023

T. maritima ThyX in complex with TyC5-03

PDB ID 5chp

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