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5ci9

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<StructureSection load='5ci9' size='340' side='right'caption='[[5ci9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5ci9' size='340' side='right'caption='[[5ci9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ci9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CI9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CI9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ci9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CI9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=549:1-(PROPAN-2-YL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC+ACID'>549</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=549:1-(PROPAN-2-YL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC+ACID'>549</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ci8|5ci8]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ci9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ci9 OCA], [https://pdbe.org/5ci9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ci9 RCSB], [https://www.ebi.ac.uk/pdbsum/5ci9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ci9 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TOB1, TOB, TROB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ci9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ci9 OCA], [http://pdbe.org/5ci9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ci9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ci9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ci9 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN]] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
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[https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bai, Y]]
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[[Category: Bai Y]]
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[[Category: Bartlam, M]]
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[[Category: Bartlam M]]
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[[Category: Nagatoishi, S]]
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[[Category: Nagatoishi S]]
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[[Category: Suzuki, T]]
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[[Category: Suzuki T]]
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[[Category: Tashiro, S]]
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[[Category: Tashiro S]]
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[[Category: Tsumoto, K]]
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[[Category: Tsumoto K]]
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[[Category: Yamamoto, T]]
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[[Category: Yamamoto T]]
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[[Category: Tob/btg family]]
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[[Category: Transcription-inhibitor complex]]
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Revision as of 12:07, 14 June 2023

Crystal structure of human Tob in complex with inhibitor fragment 6

PDB ID 5ci9

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