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5d9f

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<StructureSection load='5d9f' size='340' side='right'caption='[[5d9f]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='5d9f' size='340' side='right'caption='[[5d9f]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5d9f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haein Haein]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D9F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5d9f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D9F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=58G:6-{[(1R,3S)-3-PHENYLCYCLOPENTYL]AMINO}PYRIDINE-3-CARBOXAMIDE'>58G</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=58G:6-{[(1R,3S)-3-PHENYLCYCLOPENTYL]AMINO}PYRIDINE-3-CARBOXAMIDE'>58G</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmD, HI_0202 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=71421 HAEIN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d9f OCA], [https://pdbe.org/5d9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d9f RCSB], [https://www.ebi.ac.uk/pdbsum/5d9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d9f ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d9f OCA], [http://pdbe.org/5d9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d9f RCSB], [http://www.ebi.ac.uk/pdbsum/5d9f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d9f ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
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[https://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haein]]
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[[Category: Haemophilus influenzae Rd KW20]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bonnette, W G]]
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[[Category: Bonnette WG]]
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[[Category: Elkins, P A]]
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[[Category: Elkins PA]]
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[[Category: Madauss, K P]]
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[[Category: Madauss KP]]
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[[Category: Dimerization]]
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[[Category: S-adenosyl methionine]]
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[[Category: Sam-binding]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Trmd]]
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[[Category: Trna methyltransferase]]
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Revision as of 10:27, 21 June 2023

Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds

PDB ID 5d9f

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