2bur
From Proteopedia
(New page: 200px<br /> <applet load="2bur" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bur, resolution 1.8Å" /> '''CRYSTAL STRUCTURE OF...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2BUR is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Acinetobacter_calcoaceticus Acinetobacter calcoaceticus]] with FE and PHB as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.3 1.13.11.3]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BUR OCA]]. | + | 2BUR is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Acinetobacter_calcoaceticus Acinetobacter calcoaceticus]] with FE and PHB as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Protocatechuate_3,4-dioxygenase Protocatechuate 3,4-dioxygenase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.3 1.13.11.3]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BUR OCA]]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Acinetobacter calcoaceticus]] | [[Category: Acinetobacter calcoaceticus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| + | [[Category: Protocatechuate 3,4-dioxygenase]] | ||
[[Category: Argenio, D.A.D.]] | [[Category: Argenio, D.A.D.]] | ||
[[Category: Lipscomb, J.D.]] | [[Category: Lipscomb, J.D.]] | ||
| Line 28: | Line 29: | ||
[[Category: non-heme iron]] | [[Category: non-heme iron]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:23:19 2007'' |
Revision as of 09:18, 30 October 2007
|
CRYSTAL STRUCTURE OF WILD-TYPE PROTOCATECHUATE 3,4-DIOXYGENASE FROM ACINETOBACTER SP. ADP1 IN COMPLEX WITH 4-HYDROXYBENZOATE
Overview
The catechol dioxygenases allow a wide variety of bacteria to use aromatic, compounds as carbon sources by catalyzing the key ring-opening step. These, enzymes use specifically either catechol or protocatechuate, (2,3-dihydroxybenozate) as their substrates; they use a bare metal ion as, the sole cofactor. To learn how this family of metalloenzymes functions, a, structural analysis of designed and selected mutants of these enzymes has, been undertaken. Here we review the results of this analysis on the, nonheme ferric iron intradiol dioxygenase protocatechuate 3,4-dioxygenase.
About this Structure
2BUR is a [Protein complex] structure of sequences from [Acinetobacter calcoaceticus] with FE and PHB as [ligands]. Active as [Protocatechuate 3,4-dioxygenase], with EC number [1.13.11.3]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Biophysical analyses of designed and selected mutants of protocatechuate 3,4-dioxygenase1., Brown CK, Vetting MW, Earhart CA, Ohlendorf DH, Annu Rev Microbiol. 2004;58:555-85. PMID:15487948
Page seeded by OCA on Tue Oct 30 11:23:19 2007
Categories: Acinetobacter calcoaceticus | Protein complex | Protocatechuate 3,4-dioxygenase | Argenio, D.A.D. | Lipscomb, J.D. | Ohlendorf, D.H. | Ornston, L.N. | Valley, M.P. | Vetting, M.W. | FE | PHB | Aromatic degradation | Beta-sandwich | Dioxygenase | Mixed alpha/beta structure | Non-heme iron
