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Helicase 3D structures

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Line 32: Line 32:
**[[2is4]], [[2is6]] - EcHel II (mutant) + ADP + DNA<BR />
**[[2is4]], [[2is6]] - EcHel II (mutant) + ADP + DNA<BR />
**[[4c2t]], [[4c2u]], [[4c30]] – DrHel II + DNA - ''Deinococcus radiodurans''<br />
**[[4c2t]], [[4c2u]], [[4c30]] – DrHel II + DNA - ''Deinococcus radiodurans''<br />
 +
**[[6ppj]] – MsHel (mutant) – ''Mycobacterium smegmatis'' – Cryo EM<br />
 +
**[[6ppr]], [[6ppu]] – MsHel + DNA – Cryo EM<br />
*ATP-dependent helicase ATRX
*ATP-dependent helicase ATRX
Line 118: Line 120:
**[[2jgn]] – hDDX3X helicase domain residues 408-579<BR />
**[[2jgn]] – hDDX3X helicase domain residues 408-579<BR />
**[[3ly5]] – hDDX18 dead domain<BR />
**[[3ly5]] – hDDX18 dead domain<BR />
 +
**[[6l5l]], [[6l5o]] – hDDX21 residues 120-495 (mutant)<br />
 +
**[[6l5m]] – hDDX21 + AMP<br />
 +
**[[6l5n]] – hDDX21 + RNA<br />
**[[2rb4]] – hDDX25 helicase domain<BR />
**[[2rb4]] – hDDX25 helicase domain<BR />
**[[2p6n]] – hDDX41 helicase domain (mutant) <BR />
**[[2p6n]] – hDDX41 helicase domain (mutant) <BR />
Line 143: Line 148:
**[[3fht]] – hDBP5 + AMPPNP + RNA<BR />
**[[3fht]] – hDBP5 + AMPPNP + RNA<BR />
**[[6cz5]] - hDDX3X residues 132-607 + AMP<br />
**[[6cz5]] - hDDX3X residues 132-607 + AMP<br />
 +
**[[6o5f]] - hDDX3X + RNA<br />
**[[6b4k]] – hDDX19B residues 54-479 + ANP<br />
**[[6b4k]] – hDDX19B residues 54-479 + ANP<br />
**[[6b4j]], [[6b4i]] – hDDX19B residues 54-479 + GLE1 + Nup42 + ANP<br />
**[[6b4j]], [[6b4i]] – hDDX19B residues 54-479 + GLE1 + Nup42 + ANP<br />
Line 178: Line 184:
**[[2eqs]] – hDHX8 S1 domain residues 260-355<br />
**[[2eqs]] – hDHX8 S1 domain residues 260-355<br />
**[[3i4u]] – hDHX8 residues 950-1183<br />
**[[3i4u]] – hDHX8 residues 950-1183<br />
 +
**[[6hys]] – hDHX8 helicase domain residues 548-1220 + ATP<br />
 +
**[[6hyt]] – hDHX8 helicase domain + ADP<br />
 +
**[[6hyu]] – hDHX8 helicase domain + RNA<br />
**[[3llm]] – hDHX9<br />
**[[3llm]] – hDHX9<br />
**[[5xdr]] – hDHX15 residues 110-795 (mutant)<br />
**[[5xdr]] – hDHX15 residues 110-795 (mutant)<br />
 +
**[[6sh6]], [[6sh7]] – hDHX15 + Nfkb-repressing factor + ADP<br />
**[[2n16]] – hDHX36 G-quadruplex domain - NMR<br />
**[[2n16]] – hDHX36 G-quadruplex domain - NMR<br />
**[[2rqa]] – hDHX58 C terminal – NMR<br />
**[[2rqa]] – hDHX58 C terminal – NMR<br />
Line 279: Line 289:
*Werner syndrome ATP-dependent DNA helicase
*Werner syndrome ATP-dependent DNA helicase
-
**[[2e1e]], [[2e1f]], [[2dgz]] – hWRN HRDC domain<BR />
+
**[[2e1e]], [[2e1f]], [[2dgz]] – hWRN HRDC domain 1142-1242<BR />
-
**[[2fbt]] - hWRN exonuclease domain<BR />
+
**[[2fbt]] - hWRN exonuclease domain 38-236<BR />
**[[2fbv]], [[2fbx]], [[2fby]], [[2fc0]] - hWRN exonuclease domain + metal ion
**[[2fbv]], [[2fbx]], [[2fby]], [[2fc0]] - hWRN exonuclease domain + metal ion
-
**[[3aaf]] – hWRN C terminal + DNA<br />
+
**[[3aaf]] – hWRN C terminal 949-1079 + DNA<br />
-
**[[2e6l]], [[2e6m]]- mWRN exonuclease domain
+
**[[6yhr]] - hWRN 517-1094<br />
 +
**[[2e6l]], [[2e6m]] - mWRN exonuclease domain
*ATP-dependent DNA helicase Q
*ATP-dependent DNA helicase Q
Line 369: Line 380:
**[[5dma]] – GsPcrA C-terminal tudor domain<br />
**[[5dma]] – GsPcrA C-terminal tudor domain<br />
-
*DnaB helicase
+
*DnaB helicase or replicative DNA helicase
**[[3gxv]] – HpDnaB – ''Helicobacter pylori''<BR />
**[[3gxv]] – HpDnaB – ''Helicobacter pylori''<BR />
Line 385: Line 396:
**[[1jwe]] - EcDnaB N terminal - NMR<BR />
**[[1jwe]] - EcDnaB N terminal - NMR<BR />
**[[2r6c]], [[2r6a]] – BsDnaB + DnaG helicase-binding domain<br />
**[[2r6c]], [[2r6a]] – BsDnaB + DnaG helicase-binding domain<br />
-
**[[6bs8]] – MsDnaB <br />
+
**[[6bs8]], [[6own]] – MsDnaB 238-376<br />
 +
**[[6rix]], [[6riy]] – DnaB (mutant) – ''Mycobacterium chimaera''<br />
*DnaC helicase
*DnaC helicase
Line 406: Line 418:
**[[4w7s]] – yCa8<br />
**[[4w7s]] – yCa8<br />
-
*Helicase NSP2
+
*Helicase NSP
**[[6jim]] – NSP2 + RNA – Chicungunya virus<br />
**[[6jim]] – NSP2 + RNA – Chicungunya virus<br />
-
**[[2hwk]] – NSP2 – Venzuelan equine encephalitis virus
+
**[[2hwk]] – NSP2 – Venzuelan equine encephalitis virus<br />
 +
**[[6jyt]] – NSP13 – Human SARS-COV virus<br />
*Helicase SEN1
*Helicase SEN1

Revision as of 07:39, 16 August 2020

3D structures of helicase

Updated on 16-August-2020

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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