This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5ed6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:21, 5 July 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5ed6' size='340' side='right'caption='[[5ed6]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
<StructureSection load='5ed6' size='340' side='right'caption='[[5ed6]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5ed6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ED6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ED6 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5ed6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ED6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ED6 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ecb|5ecb]], [[5ecz|5ecz]], [[5ed3|5ed3]], [[5ed5|5ed5]], [[5ede|5ede]], [[5efl|5efl]], [[5efp|5efp]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT, PKCI1, PRKCNH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ed6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ed6 OCA], [https://pdbe.org/5ed6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ed6 RCSB], [https://www.ebi.ac.uk/pdbsum/5ed6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ed6 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ed6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ed6 OCA], [http://pdbe.org/5ed6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ed6 RCSB], [http://www.ebi.ac.uk/pdbsum/5ed6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ed6 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
+
[https://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Fang, P]]
+
[[Category: Fang P]]
-
[[Category: Guo, M]]
+
[[Category: Guo M]]
-
[[Category: Wang, J]]
+
[[Category: Wang J]]
-
[[Category: Hydrolase]]
+
-
[[Category: Nucleotide binding]]
+
-
[[Category: Regulation of transcription]]
+
-
[[Category: Signal transduction]]
+

Current revision

crystal structure of human Hint1 H114A mutant complexing with ATP

PDB ID 5ed6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ed6"
Personal tools