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6qen

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Current revision (11:58, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6qen' size='340' side='right'caption='[[6qen]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='6qen' size='340' side='right'caption='[[6qen]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6qen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QEN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6QEN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6qen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QEN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J05:1-[[1-[(4-bromophenyl)methyl]-1,2,3-triazol-4-yl]methylamino]-2-methyl-1-oxidanylidene-propane-2-sulfonic+acid'>J05</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.195&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qbu|6qbu]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J05:1-[[1-[(4-bromophenyl)methyl]-1,2,3-triazol-4-yl]methylamino]-2-methyl-1-oxidanylidene-propane-2-sulfonic+acid'>J05</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qen OCA], [https://pdbe.org/6qen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qen RCSB], [https://www.ebi.ac.uk/pdbsum/6qen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qen ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6qen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qen OCA], [http://pdbe.org/6qen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qen RCSB], [http://www.ebi.ac.uk/pdbsum/6qen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qen ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG]] Acts upon elastin.
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[https://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG] Acts upon elastin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6qen" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6qen" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Elastase 3D structures|Elastase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pancreatic elastase]]
 
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Almeida, V T]]
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[[Category: Almeida VT]]
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[[Category: Archer, M]]
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[[Category: Archer M]]
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[[Category: Brito, J A]]
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[[Category: Brito JA]]
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[[Category: Carvalho, L M]]
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[[Category: Carvalho LM]]
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[[Category: Moreira, R]]
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[[Category: Moreira R]]
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[[Category: 3-oxo-beta-sultam]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Pancreatic porcine elastase]]
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[[Category: Serine hydrolase]]
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[[Category: Sulfonylation]]
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Current revision

Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the 3-Oxo-beta-Sultam inhibitor LMC240

PDB ID 6qen

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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