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5dcg
From Proteopedia
(Difference between revisions)
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<StructureSection load='5dcg' size='340' side='right'caption='[[5dcg]], [[Resolution|resolution]] 2.01Å' scene=''> | <StructureSection load='5dcg' size='340' side='right'caption='[[5dcg]], [[Resolution|resolution]] 2.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5dcg]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5dcg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DCG FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dcg OCA], [https://pdbe.org/5dcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dcg RCSB], [https://www.ebi.ac.uk/pdbsum/5dcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dcg ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref> |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Morton | + | [[Category: Morton CJ]] |
| - | [[Category: Parker | + | [[Category: Parker LJ]] |
| - | [[Category: Parker | + | [[Category: Parker MW]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 10:30, 21 June 2023
Crystal Structure of WT Apo Human Glutathione Transferase Pi
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