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5dof

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Current revision (21:52, 28 June 2023) (edit) (undo)
 
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<StructureSection load='5dof' size='340' side='right'caption='[[5dof]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5dof' size='340' side='right'caption='[[5dof]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dof]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetth Tetth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DOF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DOF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dof]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DOF FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5doi|5doi]], [[5dok|5dok]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TAP19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5911 TETTH])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dof OCA], [https://pdbe.org/5dof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dof RCSB], [https://www.ebi.ac.uk/pdbsum/5dof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dof ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dof OCA], [http://pdbe.org/5dof PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dof RCSB], [http://www.ebi.ac.uk/pdbsum/5dof PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dof ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TAP19_TETTS TAP19_TETTS] Component of a CST-like subcomplex of the holoenzyme telomerase ribonucleoprotein complex, which stimulates telomerase complementary-strand synthesis (PubMed:26551074). Telomerase is an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:26551074). The CST-like subcomplex (also named 7-4-1) binds telomeric single-stranded DNA and coordinates telomere G-strand and C-strand synthesis (PubMed:26551074).<ref>PMID:26551074</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tetth]]
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[[Category: Tetrahymena thermophila]]
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[[Category: Lei, M]]
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[[Category: Lei M]]
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[[Category: Tang, T]]
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[[Category: Tang T]]
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[[Category: Wan, B]]
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[[Category: Wan B]]
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[[Category: Wu, J]]
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[[Category: Wu J]]
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[[Category: Dna binding protein]]
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[[Category: Ob fold]]
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[[Category: Telomerase]]
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[[Category: Tetrahymena]]
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Current revision

Crystal structure of Tetrahymena p19

PDB ID 5dof

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