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2ix8

From Proteopedia

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Current revision (10:34, 12 January 2022) (edit) (undo)
 
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<SX load='2ix8' size='340' side='right' viewer='molstar' caption='[[2ix8]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
<SX load='2ix8' size='340' side='right' viewer='molstar' caption='[[2ix8]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ix8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IX8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ix8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IX8 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ix8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix8 OCA], [http://pdbe.org/2ix8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ix8 RCSB], [http://www.ebi.ac.uk/pdbsum/2ix8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ix8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix8 OCA], [https://pdbe.org/2ix8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ix8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ix8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EF3A_YEAST EF3A_YEAST]] Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis. Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied.<ref>PMID:6456269</ref> <ref>PMID:7657623</ref>
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[[https://www.uniprot.org/uniprot/EF3A_YEAST EF3A_YEAST]] Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis. Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied.<ref>PMID:6456269</ref> <ref>PMID:7657623</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Current revision

MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME

2ix8, resolution 6.00Å

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OCA

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