2w6d

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<SX load='2w6d' size='340' side='right' viewer='molstar' caption='[[2w6d]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
<SX load='2w6d' size='340' side='right' viewer='molstar' caption='[[2w6d]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w6d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nosp7 Nosp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W6D OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W6D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w6d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nosp7 Nosp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W6D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W6D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPL:1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>CPL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPL:1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>CPL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j69|2j69]], [[2j68|2j68]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2j69|2j69]], [[2j68|2j68]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w6d OCA], [http://pdbe.org/2w6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w6d RCSB], [http://www.ebi.ac.uk/pdbsum/2w6d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w6d ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w6d OCA], [https://pdbe.org/2w6d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w6d RCSB], [https://www.ebi.ac.uk/pdbsum/2w6d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w6d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BDLP_NOSP7 BDLP_NOSP7]] Dynamin-related GTPase probably involved in membrane remodeling. Lipid and nucleotide-binding are thought to induce a large intramolecular rearrangment, leading to assembly on lipid bilayers and possible membrane curving. In the presence of the non-hydrolyzable GTP analog GMP-PNP self-assembles on a lipid bilayer; this does not stimulate subsequent GTPase activity. Does not bind lipids in the presence of GDP; perhaps GTP hydrolysis disrupts membrane-binding.<ref>PMID:17122778</ref>
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[[https://www.uniprot.org/uniprot/BDLP_NOSP7 BDLP_NOSP7]] Dynamin-related GTPase probably involved in membrane remodeling. Lipid and nucleotide-binding are thought to induce a large intramolecular rearrangment, leading to assembly on lipid bilayers and possible membrane curving. In the presence of the non-hydrolyzable GTP analog GMP-PNP self-assembles on a lipid bilayer; this does not stimulate subsequent GTPase activity. Does not bind lipids in the presence of GDP; perhaps GTP hydrolysis disrupts membrane-binding.<ref>PMID:17122778</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2w6d" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2w6d" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Dynamin 3D structures|Dynamin 3D structures]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 10:37, 12 January 2022

BACTERIAL DYNAMIN-LIKE PROTEIN LIPID TUBE BOUND

2w6d, resolution 9.00Å

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